Effect of selenium on cadmium-induced chromosomal aberrations in bone marrow cells of mice.

Selenium, which is regarded as nature's antidote to heavy metal toxicities, was administered to mice. Salt solutions of cadmium chloride and sodium selenite were gavaged singly and successively, with or without a time gap of 1 h. Degrees of protection offered by this element against cadmium-induced toxic effects with special reference to chromosomal aberrations were assessed.