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不同策略治疗晚期圆锥角膜的视力结果:巩膜镜、角膜内环段植入和板层角膜移植术。

Visual outcomes in advanced keratoconus using different strategies: Scleral lens, intracorneal ring segment and lamellar keratoplasty.

机构信息

Contact Lens Sector, Refractive Surgery and Cornea Sector, Hospital Oftalmológico de Brasília, Brasilia, Brazil.

Hospital Oftalmológico de Brasília, Brasilia, Brazil.

出版信息

Eur J Ophthalmol. 2021 Jul;31(4):1563-1570. doi: 10.1177/1120672121994731. Epub 2021 Feb 14.

Abstract

PURPOSE

To compare VA outcomes in patients with advanced keratoconus wearing SCL or after ICRS or DALK. In addition, determine the percentage of complimentary treatments after ICRS and DALK, and which of these was fitting a SCL, and final visual acuity (f-VA) results.

METHODS

Retrospective case series analyzed 55 eyes with advanced keratoconus fitted with SCL, or after ICRS or a DALK between 2010 and 2018. The variables analyzed were sex, age, UDVA, CDVA, SEQ, -readings, and f-VA after complimentary treatments.

RESULTS

Twenty-eight eyes underwent a DALK, 14 were fitted with a SCL, and other 13 underwent ICRS insertion. Patients after DALK and after ICRS showed statistically significant improvement in UDVA and CDVA after surgery, with no difference between these groups. Patients fitted with SCL showed statistically higher CDVA improvement when compared to ICRS. After DALK and ICRS, respectively, nine eyes (32.14%) and seven eyes (53.85%) were fitted with SCL. Comparison between f-VA with SCL in three groups showed that the best result was achieved in DALK + SCL, with statistically significant difference to only SCL.

CONCLUSION

We showed that the CDVA of eyes fitted with SCL without any surgical treatment was statistically better than CDVA of eyes after ICRS insertion. After DALK and ICRS insertion, many patients needed a complimentary treatment to improve CDVA. The most chosen treatment was fitting a SCL. After this, all eyes showed statistically significant improvement in f-VA, with statistically better results for DALK + SCL when compared to SCL fitted in advanced keratoconus without any surgical treatment.

摘要

目的

比较佩戴硬性透气性角膜接触镜(SCL)或行角膜交联术(ICRS)或角膜移植术后圆锥角膜进展患者的视力结果。此外,确定 ICRS 和 DALK 术后的补充治疗比例,以及这些治疗中哪些适合佩戴 SCL,以及最终的视力(f-VA)结果。

方法

回顾性病例系列分析了 2010 年至 2018 年间,55 只患有进展性圆锥角膜的眼接受了 SCL 或 ICRS 或 DALK 治疗。分析的变量包括性别、年龄、未矫正远视力(UDVA)、最佳矫正远视力(CDVA)、角膜散光(SEQ)、-读数和补充治疗后的 f-VA。

结果

28 只眼行 DALK,14 只眼佩戴 SCL,13 只眼行 ICRS 植入。DALK 和 ICRS 术后 UDVA 和 CDVA 均有统计学显著改善,两组间无差异。与 ICRS 相比,佩戴 SCL 的患者 CDVA 改善具有统计学意义。分别在 DALK 和 ICRS 后,有 9 只眼(32.14%)和 7 只眼(53.85%)需要佩戴 SCL。三组 f-VA 与 SCL 的比较显示,DALK+SCL 组获得的最佳结果具有统计学意义,与仅 SCL 组相比差异显著。

结论

我们发现,未行任何手术治疗而佩戴 SCL 的眼的 CDVA 与 ICRS 植入术后的 CDVA 相比具有统计学意义上的优势。在 DALK 和 ICRS 植入术后,许多患者需要补充治疗来提高 CDVA。最常选择的治疗方法是佩戴 SCL。在此之后,所有眼的 f-VA 均有统计学意义上的改善,与未行任何手术治疗而佩戴 SCL 的进展性圆锥角膜眼相比,DALK+SCL 组的结果具有统计学意义上的优势。

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