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深板层角膜移植术后行角膜基质环植入术矫正散光:中期和长期随访。

Intrastromal Corneal Ring Segments Implantation After Deep Anterior Lamellar Keratoplasty for Astigmatism Correction: Mid-term and Long-term Follow-up.

机构信息

Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de Oviedo, Oviedo, Spain; and.

Clinical and Experimental Eye Research Group (CEER), Faculty of Optics and Optometry, Universidad Complutense de Madrid, Spain.

出版信息

Cornea. 2023 Aug 1;42(8):962-969. doi: 10.1097/ICO.0000000000003110. Epub 2022 Aug 24.

DOI:10.1097/ICO.0000000000003110
PMID:36036677
Abstract

PURPOSE

The aim of this study was to assess the long-term outcomes of implanting intrastromal corneal ring segments (ICRSs) using a femtosecond laser for correcting astigmatism in patients who had previous deep anterior lamellar keratoplasty (DALK) throughout a 5-year follow-up period.

METHODS

This retrospective study included 40 eyes of 40 patients with previous DALK and astigmatism ≥3.00 D who underwent Ferrara-type ICRS implantation. The manifest refraction, uncorrected (UDVA) and corrected (CDVA) distance visual acuity (logMAR), and corneal topography were recorded preoperatively and at 6, 12, 36, and 60 months postoperatively.

RESULTS

The mean UDVA (logMAR scale) improved from 1.39 ± 0.55 preoperatively to 0.71 ± 0.37 at 6 months postoperatively ( P < 0.0001). The mean CDVA (logMAR) significantly improved from 0.36 ± 0.17 to 0.22 ± 0.12 at 6 months after surgery ( P < 0.0001). Both UDVA and CDVA remained unchanged throughout the follow-up ( P = 0.09). Postoperatively, no eyes lost lines of CDVA compared to preoperatively, and around 80% of the eyes gained lines of CDVA. The safety index remained stable at a value of 1.4 throughout the follow-up. The refractive cylinder decreased from -6.86 ± 2.62 D preoperatively to -2.33 ± 1.09D at 6 months postoperatively ( P < 0.0001), and subsequently, it was stable over the postoperative period ( P = 0.2). The maximum and minimum keratometry measurements significantly decreased after surgery and remained stable over the postoperative follow-up period ( P > 0.07).

CONCLUSIONS

This study shows the long-term viability of Ferrara-type ICRS implantation using a femtosecond laser as a surgical alternative for astigmatism correction in post-DALK eyes.

摘要

目的

本研究旨在评估使用飞秒激光植入间质角膜环段(ICRS)治疗既往行深板层角膜移植术(DALK)后伴≥3.00 D 散光患者的长期疗效。

方法

本回顾性研究纳入了 40 例(40 只眼)既往行 DALK 且散光≥3.00 D 的患者,所有患者均行 Ferrara 型 ICRS 植入术。记录术前、术后 6、12、36 和 60 个月的视力(包括最佳矫正视力(BCVA)和未矫正视力(UCVA))、角膜地形图和角膜曲率等参数。

结果

术后 6 个月时,患者的 UCVA(logMAR 视力表)由术前的 1.39±0.55 提高至 0.71±0.37( P < 0.0001),BCVA(logMAR)由术前的 0.36±0.17 提高至术后 6 个月的 0.22±0.12( P < 0.0001)。术后 60 个月时,两组视力均保持稳定( P = 0.09)。与术前相比,术后所有患者均未丢失 BCVA 视力,约 80%的患者获得了 BCVA 视力提高。术后安全指数(AI)一直稳定在 1.4。术后 6 个月,等效球镜(SE)由术前的-6.86±2.62 D 下降至-2.33±1.09D( P < 0.0001),术后随访期间,SE 保持稳定( P = 0.2)。术后角膜最大和最小曲率值显著下降,术后随访期间保持稳定( P > 0.07)。

结论

本研究表明,飞秒激光用于 Ferrara 型 ICRS 植入术治疗 DALK 术后散光,具有长期有效性。

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