中国东北地区鹅场分离株的流行情况及抗菌药物耐药性
Prevalence and antimicrobial resistance of isolates from goose farms in Northeast China.
作者信息
Cao Z Z, Xu J W, Gao M, Li X S, Zhai Y J, Yu K, Wan M, Luan X H
机构信息
Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, 110866, China.
MSc Student in Basic Veterinary Medicine, Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, 110866, China.
出版信息
Iran J Vet Res. 2020 Fall;21(4):287-293.
BACKGROUND
is one of the most important enteric pathogenic bacteria that threatened poultry health.
AIMS
This study aimed to investigate the prevalence and antimicrobial resistance of isolates in goose farms.
METHODS
A total of 244 cloacal swabs were collected from goose farms to detect in Northeast China. Antimicrobial susceptibility, and resistance gene distribution of isolates were investigated.
RESULTS
Twenty-one isolates were identified. Overall prevalence of in the present study was 8.6%. Among the isolates, the highest resistance frequencies belonged to amoxicillin (AMX) (85.7%), tetracycline (TET) and trimethoprim/sulfamethoxazole (SXT) (81%), followed by chloramphenicol (CHL) (76.2%), florfenicol (FLO) (71.4%), kanamycin (KAN) (47.6%), and gentamycin (GEN) (38.1%). Meanwhile, only 4.8% of the isolates were resistant to ciprofloxacin (CIP) and cefotaxime (CTX). None of the isolates was resistant to cefoperazone (CFP) and colistin B (CLB). Twenty isolates (95%) were simultaneously resistant to at least two antimicrobials. Ten resistance genes were detected among which the , , , , , , and were the most prevalent, and presented in all 21 isolates followed by (20/21), (19/21), and (15/21).
CONCLUSION
Results indicated that isolates from goose farms in Northeast China exhibited multi-drug resistance (MDR), harboring multiple antimicrobial resistance genes. Our results will be useful to design prevention and therapeutic strategies against infection in goose farms.
背景
是威胁家禽健康的最重要的肠道致病菌之一。
目的
本研究旨在调查鹅场中分离株的流行情况及耐药性。
方法
从中国东北地区的鹅场收集了244份泄殖腔拭子以检测。对分离株的药敏性及耐药基因分布进行了研究。
结果
鉴定出21株分离株。本研究中总体流行率为8.6%。在这些分离株中，耐药频率最高的是阿莫西林（AMX）（85.7%）、四环素（TET）和甲氧苄啶/磺胺甲恶唑（SXT）（81%），其次是氯霉素（CHL）（76.2%）、氟苯尼考（FLO）（71.4%）、卡那霉素（KAN）（47.6%）和庆大霉素（GEN）（38.1%）。同时，仅4.8%的分离株对环丙沙星（CIP）和头孢噻肟（CTX）耐药。没有分离株对头孢哌酮（CFP）和多粘菌素B（CLB）耐药。20株（95%）分离株同时对至少两种抗菌药物耐药。检测到10种耐药基因，其中、、、、、、最为普遍，在所有21株分离株中均有出现，其次是（20/21）、（19/21）和（15/21）。
结论
结果表明，中国东北地区鹅场的分离株表现出多重耐药性（MDR），携带多种抗菌耐药基因。我们的结果将有助于设计针对鹅场感染的预防和治疗策略。
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