Chlapoutakis Serafeim, Garmpi Anna, Trakas Nikolaos, Damaskos Christos, Georgakopoulou Vasiliki E
Department or Thoracic Surgery, Agios Savvas Hospital, Athens, GRC.
First Department of Propedeutic Internal Medicine, Laiko General Hospital, Athens Medical School, National and Kapodistrian University of Athens, Athens, GRC.
Cureus. 2021 Jan 10;13(1):e12601. doi: 10.7759/cureus.12601.
Swyer-James-Macleod syndrome is an infrequent clinical condition characterized by unilateral hyperlucent lung as a complication following infectious bronchiolitis obliterans, typically diagnosed during childhood. However, in some patients, the diagnosis may be confirmed in adulthood. The syndrome can be misdiagnosed with other lung disorders such as asthma, pulmonary embolism, and pneumothorax, leading to inappropriate management and worse outcome. We present a case of Swyer-James-MacLeod syndrome, diagnosed in a 63-year-old man, with frequent hospitalisations due to chronic obstructive pulmonary disease (COPD) exacerbations without a history of significant lung infection in childhood. Complications of Swyer-James-MacLeod syndrome include recurrent infections, lung abscess, pneumothorax, and pulmonary hypertension. The syndrome should always be considered in adults with recurrent respiratory infections or pulmonary hyperlucency on chest imaging to prevent a delay in correct diagnosis and improper treatment.
斯怀尔-詹姆斯-麦克劳德综合征是一种罕见的临床病症，其特征为单侧肺透亮度增加，是感染后闭塞性细支气管炎的并发症，通常在儿童期确诊。然而，在一些患者中，诊断可能在成年期得到证实。该综合征可能会与哮喘、肺栓塞和气胸等其他肺部疾病误诊，导致治疗不当和预后较差。我们报告一例斯怀尔-詹姆斯-麦克劳德综合征病例，该病例发生在一名63岁男性身上，因慢性阻塞性肺疾病（COPD）急性加重频繁住院，但其儿童期无严重肺部感染病史。斯怀尔-詹姆斯-麦克劳德综合征的并发症包括反复感染、肺脓肿、气胸和肺动脉高压。对于胸部影像学显示反复呼吸道感染或肺透亮度增加的成年人，应始终考虑该综合征，以防止正确诊断延误和治疗不当。
