Gong Yan, Cao Chen, Guo Yu, Chang Binge, Sheng Zhiguo, Shen Wen, Zou Ying, Lu Xiudi, Xing Jiahua, Xia Shuang
Department of Radiology, First Central Clinical College, Tianjin Medical University, Tianjin, 300192, China.
Department of Radiology, Tianjin Medical University Nankai Hospital, Tianjin, 300100, China.
Eur Radiol. 2021 Aug;31(8):5479-5489. doi: 10.1007/s00330-021-07719-x. Epub 2021 Feb 14.
The purpose of this study was to compare the reproducibility and diagnostic agreement of high-resolution vessel wall imaging (HR-VWI) and time-of-flight magnetic resonance angiography (TOF-MRA) with digital subtraction angiography (DSA) to evaluate intracranial arterial stenosis.
We retrospectively enrolled patients who underwent HR-VWI and TOF-MRA with suspected intracranial artery disease and had DSA results from our institutional imaging database. Two neuroradiologists separately and independently evaluated anonymous image data for the stenotic lesions. DSA was analyzed by two neurointerventionalists and it served as a standard criterion. The reproducibility of these two MR techniques was determined by the intraclass correlation coefficients (ICCs). The diagnostic agreement to DSA was assessed by the concordance correlation coefficients (CCCs).
A total of 246 lesions from 106 individuals were analyzed for stenotic degrees. The total intra-observer and inter-observer reproducibility of HR-VWI was excellent for identifying stenosis and better than of TOF-MRA. The overall concordance of HR-VWI with DSA was excellent with CCC = 0.932, whereas TOF-MRA was 0.694. In addition, HR-VWI could provide additional vessel wall information.
HR-VWI has more advantages over TOF-MRA, such as better reproducibilities and diagnostic agreements with DSA to analyze intracranial arterial stenosis. It provides additional information that helps in clinical diagnosis and management.
• High-resolution vessel wall imaging can assess intracranial arterial stenosis with a better reproducibility than TOF-MRA and has a higher diagnostic agreement with DSA. • High-resolution vessel wall imaging had a higher diagnostic agreement with DSA compared with TOF-MRA. • Apart from evaluating vascular stenosis, HR-VWI provided additional vessel wall information to help in clinical diagnosis.
本研究旨在比较高分辨率血管壁成像（HR-VWI）和时间飞跃磁共振血管造影（TOF-MRA）与数字减影血管造影（DSA）在评估颅内动脉狭窄方面的可重复性和诊断一致性。
我们回顾性纳入了因疑似颅内动脉疾病接受HR-VWI和TOF-MRA检查且有来自本机构影像数据库的DSA结果的患者。两名神经放射科医生分别独立评估匿名影像数据中的狭窄病变。两名神经介入医生对DSA进行分析，并将其作为标准对照。通过组内相关系数（ICC）确定这两种磁共振技术的可重复性。通过一致性相关系数（CCC）评估与DSA的诊断一致性。
共分析了106例个体的246个病变的狭窄程度。HR-VWI在识别狭窄方面的观察者内和观察者间总体可重复性极佳，优于TOF-MRA。HR-VWI与DSA的总体一致性极佳，CCC = 0.932，而TOF-MRA为0.694。此外，HR-VWI可提供额外的血管壁信息。
HR-VWI比TOF-MRA具有更多优势，例如在分析颅内动脉狭窄方面具有更好的可重复性和与DSA的诊断一致性。它提供的额外信息有助于临床诊断和管理。
• 高分辨率血管壁成像评估颅内动脉狭窄的可重复性优于TOF-MRA，与DSA的诊断一致性更高。• 与TOF-MRA相比，高分辨率血管壁成像与DSA的诊断一致性更高。• 除了评估血管狭窄外，HR-VWI还提供额外的血管壁信息以帮助临床诊断。
