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N Engl J Med. 2018 Oct 18;379(16):1499-1508. doi: 10.1056/NEJMoa1800722. Epub 2018 Sep 16.
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Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.阿司匹林用于降低心血管疾病中危患者首发血管事件风险（ARRIVE）的研究：一项随机、双盲、安慰剂对照试验。
Lancet. 2018 Sep 22;392(10152):1036-1046. doi: 10.1016/S0140-6736(18)31924-X. Epub 2018 Aug 26.
5
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.阿司匹林用于糖尿病患者一级预防的效果。
N Engl J Med. 2018 Oct 18;379(16):1529-1539. doi: 10.1056/NEJMoa1804988. Epub 2018 Aug 26.
6
Risk of Intracranial Hemorrhage From Statin Use in Asians: A Nationwide Cohort Study.亚洲人群使用他汀类药物导致颅内出血的风险：一项全国性队列研究。
Circulation. 2015 Jun 9;131(23):2070-8. doi: 10.1161/CIRCULATIONAHA.114.013046. Epub 2015 Apr 9.
7
The epidemiology of intracerebral hemorrhage in the United States from 1979 to 2008.美国 1979 年至 2008 年的脑出血流行病学。
Neurocrit Care. 2013 Aug;19(1):95-102. doi: 10.1007/s12028-012-9793-y.
8
Lipid profiles and outcome in patients treated by intravenous thrombolysis for cerebral ischemia.静脉溶栓治疗脑缺血患者的血脂谱与预后。
Neurology. 2012 Sep 11;79(11):1101-8. doi: 10.1212/WNL.0b013e3182608c82. Epub 2012 Jul 25.
9
Results of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial by stroke subtypes.强化降低胆固醇水平预防卒中（SPARCL）试验按卒中亚型划分的结果。
Stroke. 2009 Apr;40(4):1405-9. doi: 10.1161/STROKEAHA.108.534107. Epub 2009 Feb 19.
10
Effects of intense low-density lipoprotein cholesterol reduction in patients with stroke or transient ischemic attack: the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial.强化降低低密度脂蛋白胆固醇对中风或短暂性脑缺血发作患者的影响：强化降低胆固醇水平预防中风（SPARCL）试验
Stroke. 2007 Dec;38(12):3198-204. doi: 10.1161/STROKEAHA.107.493106. Epub 2007 Oct 25.

Is the Benefit of Antithrombotics and Statins Worth the Risk of Intracerebral Hemorrhage?: It Depends.

作者信息

Gutierrez Jose

机构信息

From the Department of Neurology Columbia University Irving Medical Center New York NY.

出版信息

J Am Heart Assoc. 2021 Feb;10(5):e020460. doi: 10.1161/JAHA.121.020460. Epub 2021 Feb 15.

DOI:10.1161/JAHA.121.020460
PMID:33586459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8174294/
Abstract
摘要