Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
J Infect Dis. 2021 Feb 15;223(12 Suppl 2):1-3. doi: 10.1093/infdis/jiaa738.
Since the first case of an HIV sterilizing cure was published, remarkable progress has been made in our understanding of the mechanisms behind HIV persistence. However, our goal of achieving a safe and broadly-available treatment for sustained HIV remission has proven elusive. In this supplement, we provide a series of articles reviewing the technical hurdles facing the field, key assays to measure HIV persistence and the next-generation of therapeutics for HIV remission.
自首例 HIV 绝育治愈案例发表以来，我们对 HIV 持续存在背后的机制的理解取得了显著进展。然而，我们实现安全、广泛可用的 HIV 缓解治疗的目标仍然难以企及。在本增刊中，我们提供了一系列文章，回顾了该领域面临的技术障碍、用于测量 HIV 持续存在的关键检测方法，以及用于 HIV 缓解的下一代治疗方法。
