HIV 治愈方法的探索：我们的路在何方？
The Search for an HIV Cure: Where Do We Go From Here?
机构信息
Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
出版信息
J Infect Dis. 2021 Feb 15;223(12 Suppl 2):1-3. doi: 10.1093/infdis/jiaa738.
Abstract
Since the first case of an HIV sterilizing cure was published, remarkable progress has been made in our understanding of the mechanisms behind HIV persistence. However, our goal of achieving a safe and broadly-available treatment for sustained HIV remission has proven elusive. In this supplement, we provide a series of articles reviewing the technical hurdles facing the field, key assays to measure HIV persistence and the next-generation of therapeutics for HIV remission.
摘要
自首例 HIV 绝育治愈案例发表以来，我们对 HIV 持续存在背后的机制的理解取得了显著进展。然而，我们实现安全、广泛可用的 HIV 缓解治疗的目标仍然难以企及。在本增刊中，我们提供了一系列文章，回顾了该领域面临的技术障碍、用于测量 HIV 持续存在的关键检测方法，以及用于 HIV 缓解的下一代治疗方法。
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