Tanaka Akiko, Estrera Anthony L, Safi Hazim J
McGovern Medical School, Department of Cardiothoracic and Vascular Surgery, University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.
McGovern Medical School, Department of Cardiothoracic and Vascular Surgery, University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA -
J Cardiovasc Surg (Torino). 2021 Aug;62(4):295-301. doi: 10.23736/S0021-9509.21.11825-7. Epub 2021 Feb 15.
More than four decades have passed since the modern principals to treat thoracoabdominal aortic aneurysm (TAAA) have been established. The historical challenges in repair of TAAA are represented by - and continue to be - multiorgan protection. Among all organs, the spinal cord remains one of the most vital and vulnerable. We described our current techniques of open extent II TAAA repair, including the following topics: anesthesia, intraoperative monitoring, skin incision, exposure of the TAAA, left heart bypass, graft replacement technique, intercostal artery reattachment, visceral/renal artery reconstructions, and postoperative care. We use cerebrospinal fluid drainage, distal aortic perfusion, mild passive hypothermia, sequential clamping, and visceral and renal perfusion using roller pump in all the cases for multiorgan protection. Both motor-evoked potentials and somatosensory-evoked potentials ere used to guide the conduct of intercostal artery reattachment. Our group demonstrated that the use of adjuncts has reduced the overall spinal cord ischemia rate after Extent I TAAA from 15% to less than 2% and after Extent II TAAA from 33% (50% with clamp time exceeding 40 minutes in "clamp and go" era) to less than 4%. The current standard practice of TAAA repair with adjuncts has improved outcomes, especially regarding spinal cord ischemia.
自现代治疗胸腹主动脉瘤(TAAA)的原则确立以来,已经过去了四十多年。TAAA修复术中历史上的挑战一直是多器官保护,并且现在仍然如此。在所有器官中,脊髓仍然是最重要且最脆弱的器官之一。我们描述了目前开放性II型TAAA修复的技术,包括以下主题:麻醉、术中监测、皮肤切口、TAAA暴露、左心转流、移植物置换技术、肋间动脉重新附着、内脏/肾动脉重建以及术后护理。在所有病例中,我们都使用脑脊液引流、主动脉远端灌注、轻度被动低温、序贯阻断以及使用滚压泵进行内脏和肾脏灌注来实现多器官保护。运动诱发电位和体感诱发电位均用于指导肋间动脉重新附着的操作。我们团队证明,使用辅助措施后,I型TAAA术后脊髓缺血的总体发生率从15%降至2%以下,II型TAAA术后从33%(在“阻断并完成”时代,阻断时间超过40分钟时为50%)降至4%以下。目前使用辅助措施进行TAAA修复的标准做法改善了治疗效果,尤其是在脊髓缺血方面。