Physiotherapy Department, Healthy Aging Research Laboratory, Federal University of São Carlos, São Carlos, SP, Brazil.
Physiotherapy Department, Neurofunctional Physiotherapy Laboratory, Federal University of Alfenas, Alfenas, MG, Brazil.
Arch Phys Med Rehabil. 2021 Oct;102(10):1998-2011. doi: 10.1016/j.apmr.2021.01.081. Epub 2021 Feb 13.
To investigate the effects of resistance exercise (RE) on body structure and function, activity, and participation in individuals with Parkinson Disease (PD) in the mild to moderate stages.
Medline, Embase, Web of Science, The Cochrane Library, Lilacs, and PEDro were searched from inception until June 2020 using the terms "Parkinson Disease," "Exercise," "Resistance Training," "Muscle Strength," "Cardiorespiratory Fitness," "Postural Balance," "Gait," and "Quality of Life."
We included studies conducted in individuals with PD involving RE compared with a control group. Two independent reviewers performed the selection process based on titles, abstracts, and full-text reading. In total, 270 individuals with PD were included from 10 selected studies.
Two reviewers independently extracted characteristics related to participants, intervention and control types, and results. The PEDro scale was used to assess the methodological quality, and the level of evidence was analyzed and synthesized using the Grading of Recommendation, Assessment, Development, and Evaluations approach.
The level of evidence for body structure and function was low and without effect for lower limb muscle strength; very low and with effect for upper limb muscle strength, cardiorespiratory fitness, and postural balance; and very low and without effect for flexibility after RE training. For activity, the evidence was very low and with effect for gait and very low and without effect for mobility. For participation (ie, quality of life) the evidence was very low and without effect.
Although the level of evidence was low to very low, RE was shown to promote improvements in body structure and function (upper limb muscle strength, cardiovascular function, postural balance) and activity (gait). In contrast, RE did not significantly improve participation (quality of life). However, based on the present findings, the practice of RE can be recommended for individuals with PD in the mild to moderate stages.
探讨抗阻运动（RE）对轻度至中度帕金森病（PD）患者身体结构和功能、活动和参与能力的影响。
从建库起至 2020 年 6 月，使用“Parkinson Disease”“Exercise”“Resistance Training”“Muscle Strength”“Cardiorespiratory Fitness”“Postural Balance”“Gait”和“Quality of Life”等术语，在 Medline、Embase、Web of Science、The Cochrane Library、Lilacs 和 PEDro 中进行检索。
我们纳入了涉及 RE 与对照组比较的 PD 患者的研究。两名独立的审查员根据标题、摘要和全文阅读进行选择过程。总共纳入了 10 项选定研究中的 270 名 PD 患者。
两名审查员独立提取与参与者、干预和对照组类型以及结果相关的特征。使用 PEDro 量表评估方法学质量，并使用推荐评估、发展和评估分级方法分析和综合证据水平。
身体结构和功能的证据水平为低，对下肢肌肉力量无影响；非常低，对上肢肌肉力量、心肺功能和姿势平衡有影响；非常低，对柔韧性无影响。对于活动，证据非常低，对步态有影响，对活动能力没有影响。对于参与（即生活质量），证据非常低，没有影响。
尽管证据水平较低，但抗阻运动被证明可促进身体结构和功能（上肢肌肉力量、心血管功能、姿势平衡）以及活动（步态）的改善。相反，抗阻运动对参与度（生活质量）没有显著改善。然而，根据目前的研究结果，对于轻度至中度 PD 患者，推荐进行抗阻运动。
