土耳其人群胆总管囊肿的单中心结果。

Single-Center Results of Choledochal Cysts in Turkish Population.

机构信息

Department of Gastroenterological Surgery, Health of Science University, Ankara City Hospital, Ankara, Turkey.

Departments of Pathology, Health of Science University, Ankara City Hospital, Ankara, Turkey.

出版信息

Arch Iran Med. 2021 Jan 1;24(1):43-47. doi: 10.34172/aim.2021.07.

DOI:10.34172/aim.2021.07

PMID:33588567

Abstract

BACKGROUND

Choledochal cysts are seen commonly in Asian populations, but rarely in Western populations. The pathogenesis of these premalignant lesions is not fully understood yet and the risk of malignant transformation increases with age. The overall malignancy risk is 10%-15% in East Asian countries. In this study, we aimed to present our surgical experience as a hepatobiliary center to the literature.

METHODS

We retrospectively analyzed the data from the medical records of 70 patients operated for choledochal cyst between 2008-2019.

RESULTS

Sixty-two of the 70 (89%) patients were female and 8 (11%) were male, the mean age was 45.89 ± 15.32 years. Overall, 44 (63%) patients had type I (a+b+c), 20 (28%) type V (Caroli), 2 (3%) type II, 2 (3%) type III and 2 (3%) type IVb cysts. The most common operation was cyst excision combined with hepaticojejunostomy (n: 26, 37%). The median diameter of the resected cysts was 3 cm (min- max: 1-11 cm). Malignancy was observed only in three (4%) patients with type III, type Ib, and type V cyts, who were 19, 38, and 72 years old, respectively. Mortality was not observed, morbidity was determined totally in 30 (43%) cases during early and late postoperative periods.

CONCLUSION

Type of surgery in choledochal cysts differs according to the type of the cyst. Malignancy was observed at a rate of 4% in all age groups. Although the frequency of malignancy varies, the main treatment of choice should be surgery because malignancy can be seen at a young age.

摘要

背景

胆总管囊肿在亚洲人群中较为常见，但在西方人群中很少见。这些癌前病变的发病机制尚未完全了解，并且随着年龄的增长恶性转化的风险增加。在东亚国家，整体恶性风险为 10%-15%。在这项研究中，我们旨在向文献介绍我们作为肝胆中心的手术经验。

方法

我们回顾性分析了 2008 年至 2019 年间因胆总管囊肿接受手术的 70 例患者的病历资料。

结果

70 例患者中，62 例（89%）为女性，8 例（11%）为男性，平均年龄为 45.89 ± 15.32 岁。总体而言，44 例（63%）患者为 I 型（a+b+c），20 例（28%）为 V 型（Caroli），2 例（3%）为 II 型，2 例（3%）为 III 型，2 例（3%）为 IVb 型囊肿。最常见的手术是囊肿切除联合肝肠吻合术（n：26，37%）。切除囊肿的中位直径为 3cm（min-max：1-11cm）。仅在 3 例（4%）III 型、Ib 型和 V 型囊肿患者中观察到恶性肿瘤，他们的年龄分别为 19 岁、38 岁和 72 岁。无死亡病例，术后早期和晚期总共有 30 例（43%）出现并发症。