Ta T L, Moianova S G
Nauchnye Doki Vyss Shkoly Biol Nauki. 1988(2):35-9.
The nature of neurone response of substance nigra (SN) to nociceptive stimulation of the cat's peroneal nerve has been studied. The recording of neurone SN firing rate revealed that the majority (71.0%) of the SN neurones responded to the nociceptive repetitive stimulation of the peroneal nerve. But the thresholds of nociceptive activation in SN neurones turned to be very high. As a result of it the number of SN neurones responding to repetitive peroneal stimulation was twice as many as the number of cells responding to single stimulation of the nerve. The intravenous injection of naloxone in dose 1.0 mg/kg changed both excitatory and inhibitory responses in majority (71.4%) of SN neurones responding to repetitive peroneal stimulation. Naloxone did not modify the firing rate of neurones nonresponsive to nociception.
对猫的腓总神经进行伤害性刺激时，中脑黑质（SN）神经元的反应特性已得到研究。对SN神经元放电率的记录显示，大多数（71.0%）的SN神经元对腓总神经的伤害性重复刺激有反应。但SN神经元的伤害性激活阈值非常高。因此，对腓总神经重复刺激有反应的SN神经元数量是对该神经单次刺激有反应的细胞数量的两倍。静脉注射1.0mg/kg剂量的纳洛酮改变了大多数（71.4%）对腓总神经重复刺激有反应的SN神经元的兴奋和抑制反应。纳洛酮并未改变对伤害性刺激无反应的神经元的放电率。
