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新型钬光纤激光的初步临床经验:前 50 例。

Initial clinical experience with the new thulium fiber laser: first 50 cases.

机构信息

Sorbonne University GRC Urolithiasis No. 20 Tenon Hospital, 75020, Paris, France.

Department of Urology AP-HP, Tenon Hospital, Sorbonne University, 75020, Paris, France.

出版信息

World J Urol. 2021 Oct;39(10):3945-3950. doi: 10.1007/s00345-021-03616-6. Epub 2021 Feb 15.

Abstract

OBJECTIVE

To evaluate the efficacy, safety, and laser settings of thulium fiber laser (TFL) in laser lithotripsy during retrograde intrarenal surgery (RIRS) for ureteral and renal stones.

METHODS

A prospective study of the first 50 patients with ureteral and renal stones who underwent RIRS using TFL (SOLTIVE Premium, Olympus, Japan) was performed. 200 and 150 µm laser fibers were used for ureteral and renal stones, respectively. Stone size, stone density, laser-on time (LOT), and laser settings were recorded. We also assessed the ablation speed (mm/s), laser power (W), and Joules/mm values for each lithotripsy.

RESULTS

A total of 50 patients were included in the study with a median (IQR) age of 66 (55.5-74) years old for patients with ureteral stones and 55 (44-61.5) years old for patients with renal stones. Most of the patients had a Charlson comorbidity index score of 0. Median (IQR) stone volume for ureteral stones was 486 (332-1250) mm and for renal stones was 1800 (682.8-2760) mm. Median (IQR) stone density for ureteral and renal stones was 998 (776-1300) HU and 1200 (750-1300) HU, respectively. Median (IQR) pulse energy for ureteral stones was 0.4 (0.2-0.4) J; and for renal stones, 0.3 (0.2-0.6) J. Median pulse frequency, laser power, and laser operative time were higher in the renal stones group. The overall complication rate was low in both groups.

CONCLUSION

TFL is a safe and effective modality for lithotripsy during RIRS with minimal complication rates.

摘要

目的

评估钬纤维激光(TFL)在逆行性肾内手术(RIRS)治疗输尿管和肾结石激光碎石术中的疗效、安全性和激光设置。

方法

对 50 例接受 TFL(日本奥林巴斯 SOLTIVE Premium)行 RIRS 的输尿管和肾结石患者进行前瞻性研究。分别使用 200µm 和 150µm 激光光纤进行输尿管和肾结石碎石术。记录结石大小、结石密度、激光开启时间(LOT)和激光设置。我们还评估了每次碎石术的消融速度(mm/s)、激光功率(W)和焦耳/mm 值。

结果

共有 50 例患者纳入研究,输尿管结石患者的中位(IQR)年龄为 66(55.5-74)岁,肾结石患者的中位(IQR)年龄为 55(44-61.5)岁。大多数患者的 Charlson 合并症指数评分为 0 分。输尿管结石的中位(IQR)结石体积为 486(332-1250)mm,肾结石为 1800(682.8-2760)mm。输尿管和肾结石的中位(IQR)结石密度分别为 998(776-1300)HU 和 1200(750-1300)HU。输尿管结石的中位(IQR)脉冲能量为 0.4(0.2-0.4)J;肾结石为 0.3(0.2-0.6)J。肾结石组的中位脉冲频率、激光功率和激光手术时间较高。两组的总体并发症发生率均较低。

结论

TFL 是一种安全有效的 RIRS 碎石术方法,并发症发生率低。

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