Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University/The Miriam Hospital, Providence, Rhode Island, USA.
Department of Psychiatry and Behavioral Sciences, University of Southern California, Los Angeles, California, USA.
Int J Eat Disord. 2021 May;54(5):893-897. doi: 10.1002/eat.23484. Epub 2021 Feb 16.
In adults, pain is prospectively associated with overweight/obesity and concurrently associated with dysregulated eating, with evidence for stronger associations in women than men. This study aimed to evaluate whether similar associations among pain response, BMI, and loss of control (LOC) eating are also evident in adolescent girls.
Girls (n = 202) completed the cold pressor test (CPT) at age 10, and BMI and LOC eating were assessed annually from ages 10-16 years. Generalized linear models were used to test associations between pain tolerance (total immersion time) and threshold (latency to highest pain rating), and changes in BMI and LOC eating.
Lower pain tolerance and threshold at age 10 were associated with increases in LOC eating from age 10 to 16 (tolerance: B < -.01, SE < .01, p = .005; threshold: B = -.03, SE = .01, p = .0118). No significant associations were observed between pain tolerance/threshold and increasing BMI.
Pain responsivity in childhood is associated with increases in dysregulated eating from childhood to adolescence. These findings provide support for the early development of an interface between pain and eating behaviors.
在成年人中，疼痛与超重/肥胖呈前瞻性相关，与饮食失调呈同时相关，且女性的相关性强于男性。本研究旨在评估在青少年女孩中，疼痛反应、BMI 和失控（LOC）进食之间是否也存在类似的关联。
女孩（n=202）在 10 岁时完成冷压测试（CPT），并在 10-16 岁期间每年评估 BMI 和 LOC 进食。使用广义线性模型来检验疼痛耐受（总浸没时间）和阈值（疼痛评分最高时的潜伏期）与 BMI 和 LOC 进食变化之间的关联。
10 岁时疼痛耐受和阈值较低与 10 岁至 16 岁期间 LOC 进食增加有关（耐受：B<0.01，SE<0.01，p=0.005；阈值：B=-0.03，SE=0.01，p=0.0118）。疼痛耐受/阈值与 BMI 增加之间没有显著关联。
儿童时期的疼痛反应与儿童期到青春期饮食失调的增加有关。这些发现为疼痛和饮食行为之间早期发展的界面提供了支持。
