Choi Karmel Wong, Somers Tamara J, Babyak Michael A, Sikkema Kathleen J, Blumenthal James A, Keefe Francis J
Pain Res Manag. 2014 Nov-Dec;19(6):e159-63. doi: 10.1155/2014/598382. Epub 2014 Jun 9.
Osteoarthritis (OA) patients who are overweight or obese report higher levels of pain compared with their normal-weight OA counterparts. Evidence suggests that overweight or obese OA patients also experience pain relief from eating foods high in calories, fat or sugar. Eating to alleviate pain may be problematic because it can lead to additional weight gain, which may contribute to heightened pain.
To investigate the relationship between pain and food intake using ecological momentary assessments in a sample of 71 overweight and obese OA patients.
Participants completed two consecutive days of diary entries in which they recorded their levels of pain, mood and food intake throughout the day. Data were analyzed using generalized estimating equations that modelled pain as a predictor of calorie, fat and sugar intake. All models were adjusted for sex, body mass index, negative mood, time and treatment history.
Pain significantly predicted calorie (Z=2.57; P=0.01) and fat intake (Z=1.99; P=0.05).
Using ecological momentary assessments as a novel approach, the present study provides preliminary data supporting a relationship between pain and food intake among overweight and obese OA patients. Continued advances in our understanding of the relationship between pain and eating behaviour may help to optimize intervention strategies for these patients.
与体重正常的骨关节炎（OA）患者相比，超重或肥胖的OA患者报告的疼痛程度更高。有证据表明，超重或肥胖的OA患者通过食用高热量、高脂肪或高糖食物也能缓解疼痛。通过进食来缓解疼痛可能存在问题，因为这会导致体重进一步增加，而体重增加可能会加重疼痛。
在71名超重和肥胖的OA患者样本中，使用生态瞬时评估法研究疼痛与食物摄入量之间的关系。
参与者连续两天完成日记记录，记录他们全天的疼痛程度、情绪和食物摄入量。使用广义估计方程对数据进行分析，将疼痛作为卡路里、脂肪和糖摄入量的预测指标进行建模。所有模型均对性别、体重指数、负面情绪、时间和治疗史进行了调整。
疼痛显著预测了卡路里摄入量（Z=2.57；P=0.01）和脂肪摄入量（Z=1.99；P=0.05）。
本研究采用生态瞬时评估法这一新颖方法，提供了初步数据，支持超重和肥胖的OA患者疼痛与食物摄入量之间存在关联。我们对疼痛与饮食行为之间关系的理解不断取得进展，这可能有助于优化针对这些患者的干预策略。
