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[家庭医生中新型冠状病毒感染的临床和流行病学特征:一项病例对照研究]

[Clinical and epidemiological characteristics of SARS-CoV-2 infections in family physicians: A case-control study].

作者信息

Párraga Martínez Ignacio, Pérula de Torres Luis Angel, González Lama Jesús, Jiménez García Celia, Sánchez Montero Rosa, Rider Garrido Faustino

机构信息

Sección de Investigación de la Sociedad Española de Medicina Familiar y Comunitaria (semFYC), Centro de Salud Zona VIII de Albacete, Gerencia Atención Integrada de Albacete, Facultad de Medicina de Albacete, Universidad de Castilla-La Mancha, Albacete, España.

Atención Primaria de Salud (APS), Unidad Docente Multiprofesional de Atención Familiar y Comunitaria de Córdoba, Grupo de evaluación y mejora del PAPPS-semFYC, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofía, Universidad de Córdoba, Córdoba, España.

出版信息

Aten Primaria. 2021 Mar;53(3):101956. doi: 10.1016/j.aprim.2020.12.001. Epub 2020 Dec 17.

DOI:10.1016/j.aprim.2020.12.001
PMID:33592533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7746083/
Abstract

OBJECTIVE

To identify the sociodemographic, clinical and epidemiological characteristics associated with the presence of infection by the SARS-CoV-2 virus in family physicians who carry out their work in Primary Care (PC) or in Hospital Emergencies.

DESING

Observational analytical case-control study. SITE: Primary care.

PARTICIPANTS

969 Primare Care Physicians, Hospital Emergency physicians and other extrahospitalry centers that had PCR for the detection of the SARS-CoV-2. Of these, 133 participated as cases (PCR positive) and 836 as controls (PCR negative).

INTERVENTIONS

No.

MAIN MEASUREMENTS

Sociodemographic and work, contact with a COVID-19 patient, symptoms present during the process, first manifested symptom, previous chronic pathologies, and tobacco use.

RESULTS

13.7% (95% CI: 11.6-16.0) were cases infected with SARS-CoV-2. The most frequently declared symptoms by those infected were a feeling of fatigue/tiredness (69.2%; 95% CI: 60.9-77.4%), cough (56.4%; 95% CI: 47.6-65.2%) and headache (55.6%; 95% CI: 46.8-64.4%).Using logistic regression, the variables independently associated with SARS-CoV-2 virus infection in Family Physicians were: previous contact with a COVID-19 patient (OR: 2.3; 95% CI: 1.2-4.2), present fatigue / tiredness (OR: 2.2; 95% CI: 1.2-3.9), smell alteration (4.6; 95% CI: 1.7-12.5), taste alteration (OR: 32.0; 95% CI: 9.6-106.8), cough (OR: 3.0; 95% CI: 1.7-5.3) and fever (OR: 6.1; 95% CI: 3.2-11.4).

CONCLUSIONS

Symptoms independently related to SARS-CoV-2 virus infection in Family Physicians were fatigue, fever, cough, and altered taste and smell. The presence of these symptoms could facilitate the diagnosis of suspected COVID-19 disease and the earlier selection of those that require confirmatory tests.

摘要

目的

确定在基层医疗(PC)或医院急诊部门工作的家庭医生中,与感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒相关的社会人口统计学、临床和流行病学特征。

设计

观察性分析病例对照研究。

地点

基层医疗。

参与者

969名基层医疗医生、医院急诊医生和其他进行SARS-CoV-2检测的院外中心工作人员。其中,133人作为病例(PCR阳性),836人作为对照(PCR阴性)。

干预措施

无。

主要测量指标

社会人口统计学和工作情况、与新冠肺炎患者的接触情况、病程中出现的症状、首发症状、既往慢性病史以及吸烟情况。

结果

13.7%(95%置信区间:11.6-16.0)为感染SARS-CoV-2的病例。感染者最常报告的症状是疲劳/疲倦感(69.2%;95%置信区间:60.9-77.4%)、咳嗽(56.4%;95%置信区间:47.6-65.2%)和头痛(55.6%;95%置信区间:46.8-64.4%)。使用逻辑回归分析,家庭医生中与SARS-CoV-2病毒感染独立相关的变量为:既往与新冠肺炎患者接触(比值比:2.3;95%置信区间:1.2-4.2)、当前疲劳/疲倦(比值比:2.2;95%置信区间:1.2-3.9)、嗅觉改变(4.6;95%置信区间:1.7-12.5)、味觉改变(比值比:32.0;95%置信区间:9.6-106.8)、咳嗽(比值比:3.0;95%置信区间:1.7-5.3)和发热(比值比:6.1;95%置信区间:3.2-11.4)。

结论

家庭医生中与SARS-CoV-2病毒感染独立相关的症状为疲劳、发热、咳嗽以及味觉和嗅觉改变。这些症状的出现有助于疑似新冠肺炎疾病的诊断,并能更早地筛选出需要进行确诊检测的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d60/7893432/3af8c62a60d0/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d60/7893432/3af8c62a60d0/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d60/7893432/3af8c62a60d0/fx1.jpg

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