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基层医疗患者的长期新冠症状及相关因素:EPICOVID-AP21研究

Long COVID Symptomatology and Associated Factors in Primary Care Patients: The EPICOVID-AP21 Study.

作者信息

Romero-Rodríguez Esperanza, Perula-de-Torres Luis Ángel, González-Lama Jesús, Castro-Jiménez Rafael Ángel, Jiménez-García Celia, Priego-Pérez Carmen, Vélez-Santamaría Rodrigo, Simón-Vicente Lucía, González-Santos Josefa, González-Bernal Jerónimo J

机构信息

Maimonides Institute for Biomedical Research of Córdoba (IMIBIC), Reina Sofía University Hospital, Córdoba University, 14004 Córdoba, Spain.

Multiprofessional Family and Community Care Teaching Unit of Córdoba, 14011 Córdoba, Spain.

出版信息

Healthcare (Basel). 2023 Jan 11;11(2):218. doi: 10.3390/healthcare11020218.

DOI:10.3390/healthcare11020218
PMID:36673587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9858944/
Abstract

Persistent COVID-19 condition includes a wide variety of symptoms and health problems of indeterminate duration. The present study examined the sociodemographic and clinical characteristics of the population with Long COVID seen in Primary Care using a questionnaire based on the existing scientific literature. It was an observational and descriptive study of the characteristics of the Spanish population with Long COVID over 14 years of age. The responses were analysed by means of a descriptive analysis of the variables recorded, in addition to a bivariate analysis to determine the existence of a relationship between persistent COVID-19 and variables such as gender, age, vaccination status or concomitant pathology. The results obtained clearly describe the sociodemographic characteristics of the population, highlighting the predominance of female gender and the prevalence of tiredness and fatigue. Furthermore, relevant information was obtained on the differences in symptomatology according to gender, age, previous pathologies and alterations derived from infection and/or vaccination. These data are important for better detection, diagnosis and treatment of Long COVID and the improvement of the quality of life of this population.

摘要

持续性新冠病毒感染状况包括各种症状和持续时间不确定的健康问题。本研究使用基于现有科学文献的问卷,调查了在初级保健机构中出现长期新冠症状的人群的社会人口学和临床特征。这是一项针对14岁以上西班牙长期新冠病毒感染人群特征的观察性描述性研究。除了进行双变量分析以确定持续性新冠病毒感染与性别、年龄、疫苗接种状况或伴随疾病等变量之间的关系外,还通过对记录变量的描述性分析对回答进行了分析。所获得的结果清楚地描述了该人群的社会人口学特征,突出了女性的主导地位以及疲劳和乏力的普遍性。此外,还获得了有关根据性别、年龄、既往疾病以及感染和/或疫苗接种引起的症状差异的相关信息。这些数据对于更好地检测、诊断和治疗长期新冠病毒感染以及改善该人群的生活质量非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/522c/9858944/8a34fba9a774/healthcare-11-00218-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/522c/9858944/aee56b78c290/healthcare-11-00218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/522c/9858944/8a34fba9a774/healthcare-11-00218-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/522c/9858944/aee56b78c290/healthcare-11-00218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/522c/9858944/8a34fba9a774/healthcare-11-00218-g002.jpg

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本文引用的文献

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Global prevalence of chronic fatigue syndrome among long COVID-19 patients: A systematic review and meta-analysis.新冠长期患者中慢性疲劳综合征的全球患病率:一项系统评价和荟萃分析。
Biopsychosoc Med. 2022 Oct 23;16(1):21. doi: 10.1186/s13030-022-00250-5.
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Effect of COVID-19 Vaccines on Reducing the Risk of Long COVID in the Real World: A Systematic Review and Meta-Analysis.新冠疫苗对降低真实世界中长新冠风险的效果:系统评价和荟萃分析。
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Characteristics of long-COVID among older adults: a cross-sectional study.
长新冠的神经精神表现:临床方面与治疗方法的叙述性综述
Life (Basel). 2025 Mar 11;15(3):439. doi: 10.3390/life15030439.
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[Long-term persistence of post-COVID-19 symptoms: A two-year follow-up of a Primary Care cohort].[新冠后症状的长期持续:一项初级保健队列的两年随访]
An Sist Sanit Navar. 2025 Mar 12;48(1):e1101. doi: 10.23938/ASSN.1101.
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Association between Mexican vaccination schemes and the duration of long COVID syndrome symptoms.墨西哥疫苗接种方案与新冠后综合征症状持续时间之间的关联。
Sci Rep. 2025 Feb 12;15(1):5301. doi: 10.1038/s41598-024-59954-z.
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Caring for Long Covid patients in primary healthcare: a cross-sectional study on general practitioners' knowledge, perception and experience in Belgium and Malta.初级保健中对长期新冠患者的护理:比利时和马耳他全科医生的知识、看法和经验的横断面研究。
BMC Prim Care. 2024 Oct 21;25(1):375. doi: 10.1186/s12875-024-02617-9.
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Functionality, physical activity, fatigue and quality of life in patients with acute COVID-19 and Long COVID infection.急性 COVID-19 和长新冠感染患者的功能、体力活动、疲劳和生活质量。
Sci Rep. 2023 Nov 14;13(1):19907. doi: 10.1038/s41598-023-47218-1.
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Clinical Characterization of the Persistent COVID-19 Symptoms: A Descriptive Observational Study in Primary Care.持续性 COVID-19 症状的临床特征:初级保健中的描述性观察研究。
J Prim Care Community Health. 2023 Jan-Dec;14:21501319231208283. doi: 10.1177/21501319231208283.
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J Neurol. 2022 Aug;269(8):3990-3999. doi: 10.1007/s00415-022-11141-8. Epub 2022 Apr 30.
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Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study.英国一项前瞻性观察研究:长新冠的临床特征及炎症特征分析及其与住院后 1 年康复的关系。
Lancet Respir Med. 2022 Aug;10(8):761-775. doi: 10.1016/S2213-2600(22)00127-8. Epub 2022 Apr 23.