中药治疗失眠的有效性比较：系统评价和贝叶斯网络荟萃分析方案。
Effectiveness comparisons of Chinese patent medicine on insomnia: A protocol for systematic review and Bayesian network meta-analysis.
机构信息
College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan.
Xintai Affiliated Hospital of Shandong First Medical University, Taian, Shandong Province, PR China.
出版信息
Medicine (Baltimore). 2021 Feb 5;100(5):e24446. doi: 10.1097/MD.0000000000024446.
BACKGROUND
In recent years, the incidence of insomnia is increasing. However, the existing therapy methods for cannot fundamentally treat the disease. Meanwhile, Chinese patent medicine (CPM) plays an active role in the treatment of insomnia. However, there is no comparison and ranking of the efficacy of every CPM. Therefore, our study will use network meta-analysis to compare the efficacy of different CPM on insomnia, in order to provide evidence-based medical evidence for clinical treatment.
METHODS
We will search CNKI, Wanfang, VIP, CBM, Pubmed, Cochrane Library, Embase for the randomized controlled trials of CPM in the treatment of insomnia (up to December 31, 2020). We will use RevMan5.3, Stata15.1 and ADDIS software for statistical analysis. We will draw the surface under cumulative ranking area to predict the order of efficacy.
RESULTS
We aim to rank the efficacy and safety of different CPM for the treatment of insomnia.
CONCLUSION
CPM plays a positive role in the treatment of insomnia and can provide evidence support for clinicians and patients.
INPLASY REGISTRATION NUMBER
INPLASY2020120121.
背景
近年来，失眠的发病率不断上升。然而，现有的治疗方法并不能从根本上治疗这种疾病。同时，中药（CPM）在治疗失眠方面发挥着积极的作用。然而，对于每一种 CPM 的疗效并没有进行比较和排名。因此，我们的研究将使用网络荟萃分析来比较不同 CPM 治疗失眠的疗效，为临床治疗提供循证医学证据。
方法
我们将检索中国知网、万方、维普、中国生物医学文献数据库、PubMed、Cochrane 图书馆、Embase 中关于 CPM 治疗失眠的随机对照试验（截至 2020 年 12 月 31 日）。我们将使用 RevMan5.3、Stata15.1 和 ADDIS 软件进行统计分析。我们将绘制累积排序面积下的表面，以预测疗效的顺序。
结果
我们旨在对不同 CPM 治疗失眠的疗效和安全性进行排名。
结论
CPM 在治疗失眠方面发挥着积极的作用，可以为临床医生和患者提供证据支持。
INPLASY 注册号：INPLASY2020120121。
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