Department of Breast Surgery.
Department of Pathology, First Hospital of Jilin University, Changchun, People's Republic of China.
Medicine (Baltimore). 2021 Feb 5;100(5):e24461. doi: 10.1097/MD.0000000000024461.
Adenomyoepithelioma (AME) is a rare biphasic tumor consisting of epithelial and Myoepithelial cell. Most of the AME is benign, and only a few will progress to malignancy, Here, we report a case of low-grade malignant adenomyoepithelioma, and review the related literature, in a bid to investigate its clinical and pathological features and thus, enhance our understanding of this tumor.
A 64-year-old woman visited our hospital with a 1-year history of a painless mass in her left breast. Physical examination revealed a palpable painless mass, measuring approximately 4.5 cm, in the left breast.
Histological examination confirmed the diagnosis of malignant adenomyoepithelioma.
The patient underwent local excision of the mass, with frozen section analysis revealing ductal carcinoma in situ. Mastectomy and sentinel lymph node biopsy were then performed.
We conducted a one-year follow-up, and relapse was not observed.
Treatment of AME remains controversial owing to the lack of high volume data and absence of prospective studies. Simple mastectomy is an acceptable treatment of this tumor.
腺肌上皮瘤（AME）是一种由上皮和肌上皮细胞组成的罕见双相性肿瘤。大多数 AME 为良性，仅有少数会进展为恶性。在此，我们报告一例低级别恶性腺肌上皮瘤，并复习相关文献，旨在探讨其临床和病理特征，从而加深对该肿瘤的认识。
一位 64 岁女性因左乳无痛性肿块 1 年就诊于我院。体格检查发现左乳可触及一约 4.5cm 大小的无痛性肿块。
组织学检查证实为恶性腺肌上皮瘤。
患者接受了肿块的局部切除术，冷冻切片分析显示为导管原位癌。随后进行了乳房切除术和前哨淋巴结活检。
我们进行了为期 1 年的随访，未观察到复发。
由于缺乏大量数据和前瞻性研究，AME 的治疗仍存在争议。单纯乳房切除术是治疗该肿瘤的一种可接受的方法。
