Department of Emergency Medicine, Laboratory of Emergency Medicine, West China Hospital, and Disaster Medical Center.
School of Nursing, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Medicine (Baltimore). 2021 Feb 5;100(5):e24548. doi: 10.1097/MD.0000000000024548.
Falls can easily lead to serious injury and even death in the older adults. Many exercise interventions, such as balance, flexibility, and endurance training have been shown to reduce the incidence of falls in this population. However, which mode of exercise is most beneficial for them remains unanswered.
We will search the following databases as data sources: PUBMED, EMBASE, Cochrane Library, Wanfang, China knowledge Network (CNKI), Clinical Trials Database, and Science Network. Data extraction will be performed by two independent reviewers, who will discuss and resolve any differences, with the consensus of a third author. The RCTs will be selected according to prespecified inclusion criteria. The main outcome is the occurrence of a fall, and the secondary outcomes are the adverse consequences of a fall and a fall risk assessment index. If the heterogeneity test shows slight or no statistical heterogeneity, a fixed effect model will be used for data synthesis; otherwise, a random effect model will be used. We will develop a unified data extraction table including a number of parameters. The Cochrane cooperative bias risk tool will be used to evaluate the methodological quality of the selected RCTs. RevMan Manager v5.3 software and STATA v16.0 software will be used for data analysis. If enough randomized controlled trials (more than 10) are identified and selected.
This protocol will be applied to synthesize the existing evidence so as to identify the most effective exercise program to prevent falls in the elderly.
INPLASY2020110008.
跌倒容易导致老年人严重受伤甚至死亡。许多运动干预措施，如平衡、柔韧性和耐力训练，已被证明可降低该人群的跌倒发生率。然而，哪种运动模式对他们最有益仍未得到解答。
我们将以下数据库作为数据源进行搜索：PUBMED、EMBASE、Cochrane 图书馆、万方、中国知识网络（CNKI）、临床试验数据库和科学网。数据提取将由两名独立的审稿人进行，他们将讨论并解决任何分歧，并由第三位作者达成共识。将根据预设的纳入标准选择 RCT。主要结局是跌倒的发生，次要结局是跌倒的不良后果和跌倒风险评估指数。如果异质性检验显示轻微或无统计学异质性，则使用固定效应模型进行数据合成；否则，使用随机效应模型。我们将制定一个统一的数据提取表，其中包含许多参数。将使用 Cochrane 协作偏倚风险工具评估所选 RCT 的方法学质量。RevMan Manager v5.3 软件和 STATA v16.0 软件将用于数据分析。如果确定并选择了足够数量的随机对照试验（超过 10 个）。
本方案将用于综合现有证据，以确定预防老年人跌倒最有效的运动方案。
INPLASY 注册号：INPLASY2020110008。
