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Quantitative studies of enkephalin's coexistence with gamma-aminobutyric acid, glycine and neurotensin in amacrine cells of the chicken retina.

作者信息

Watt C B, Li T, Lam D M, Wu S M

机构信息

Center for Biotechnology, Baylor College of Medicine, Woodlands, TX 77381.

出版信息

Brain Res. 1988 Mar 22;444(2):366-70. doi: 10.1016/0006-8993(88)90948-1.

DOI:10.1016/0006-8993(88)90948-1
PMID:3359302
Abstract

Previous double-label studies demonstrate that enkephalin coexists with gamma-aminobutyric acid, glycine or neurotensin in amacrine cells of the chicken retina. The present study utilizes double- and triple-label paradigms to quantitatively analyze these coexisting relationships. Twenty-eight percent of enkephalin-like immunoreactive amacrine cells were found to exhibit high-affinity uptake of [3H]GABA, while 53% of enkephalin-amacrine cells specifically accumulate [3H]glycine. Moreover, the present study predicts that at least 26% of enkephalin-amacrine cells which accumulate [3H]glycine should also be immunoreactive for neurotensin.

摘要

相似文献

1
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