Zarka M, Tretarre B, Rebillard X, Murez T, Daures J P, Azria D, Serre I, Brel D, Ramay A S, Reis Borges R, Gevorgyan A, Hutin M, Marchal S, Korahanis N, Iborra F, Thuret R
Service d'urologie et transplantation rénale, CHU Montpellier Lapeyronie, 371, avenue du Doyen Gaston-Giraud, 34090 Montpellier, France.
Registre des tumeurs de l'Hérault, Montpellier, France.
Prog Urol. 2021 Apr;31(5):282-292. doi: 10.1016/j.purol.2020.08.054. Epub 2021 Feb 13.
The objective of this study is to present the history of cancers of the external genital organs of male in Hérault using data from the Hérault tumor register (RTH) over a period of 30 years.
Using the RTH database, we studied the development of testicular germ cell tumors (TGCT) and penile cancer (PC) over 30 years, from 1987 to 2016. We analyzed the incidence and mortality data for these tumors. We compared these results to French, European and global data.
In 30 years of registration we have recorded 725 cases of TGCT and 175 cases of PC. The age standardized incidence rate (ASR) of TGCT has doubled between 1987 and 2016 (4.2 per 100,000 in 1987 and 9.3 per 100,000 in 2016). It was multiplied by 2.63 in the population of patients aged 30 to 44. There is a decrease of the mortality rate with a ASR of 0.8 deaths per 100,000 in 1987, and 0.4/100 000 in 2016. The PC incidence ASR was stable between 1987 and 2016 (0.4-0.9/100,000). Mortality is stable with a ASR between 0.1 and 0.3 deaths per 100,000 between 1987 and 2016.
The incidence of TGCT has increased sharply in the Hérault over the past 30 years, while a decrease in mortality has been observed. The proportion of seminomas is increasing; it has gone from 53 % to 60 % in 30 years in the Hérault. The incidence and mortality of PC shows a stability in the Hérault over the past 30 years.
本研究的目的是利用埃罗省肿瘤登记处（RTH）30年的数据，呈现该省男性外生殖器癌症的发病情况。
我们使用RTH数据库，研究了1987年至2016年30年间睾丸生殖细胞肿瘤（TGCT）和阴茎癌（PC）的发病情况。我们分析了这些肿瘤的发病率和死亡率数据，并将这些结果与法国、欧洲和全球数据进行了比较。
在30年的登记中，我们记录了725例TGCT和175例PC。1987年至2016年期间，TGCT的年龄标准化发病率（ASR）翻了一番（1987年为每10万人4.2例，2016年为每10万人9.3例）。在30至44岁的患者群体中，该发病率增长了2.63倍。死亡率有所下降，1987年ASR为每10万人0.8例死亡，2016年为每10万人0.4例死亡。1987年至2016年期间，PC发病率ASR保持稳定（每10万人0.4 - 0.9例）。死亡率稳定，1987年至2016年期间ASR为每10万人0.1至0.3例死亡。
在过去30年里，埃罗省TGCT的发病率急剧上升，同时死亡率有所下降。精原细胞瘤的比例在增加，在埃罗省30年内从53%升至60%。过去30年里，埃罗省PC的发病率和死亡率保持稳定。
