Morais Filho Alcivan Batista de, Rego Thiago Luis de Holanda, Mendonça Letícia de Lima, Almeida Sulyanne Saraiva de, Nóbrega Mariana Lima da, Palmieri Thais de Oliveira, Giustina Gabriela Zanotto Della, Melo Jáderson Pimenta, Pinheiro Francisco Irochima, Guzen Fausto Pierdoná
Universidade do Estado do Rio Grande do Norte, Mossoró, Brazil.
Universidade Federal do Rio Grande do Norte, Natal, Brazil.
Rev Neurosci. 2021 Feb 17;32(6):631-658. doi: 10.1515/revneuro-2020-0131. Print 2021 Aug 26.
Hemorrhagic stroke (HS) is a major cause of death and disability worldwide, despite being less common, it presents more aggressively and leads to more severe sequelae than ischemic stroke. There are two types of HS: Intracerebral Hemorrhage (ICH) and Subarachnoid Hemorrhage (SAH), differing not only in the site of bleeding, but also in the mechanisms responsible for acute and subacute symptoms. This is a systematic review of databases in search of works of the last five years relating to the comprehension of both kinds of HS. Sixty two articles composed the direct findings of the recent literature and were further characterized to construct the pathophysiology in the order of events. The road to the understanding of the spontaneous HS pathophysiology is far from complete. Our findings show specific and individual results relating to the natural history of the disease of ICH and SAH, presenting common and different risk factors, distinct and similar clinical manifestations at onset or later days to weeks, and possible complications for both.
出血性中风（HS）是全球范围内死亡和残疾的主要原因，尽管其不如缺血性中风常见，但它进展更为迅猛，且比缺血性中风会导致更严重的后遗症。出血性中风有两种类型：脑出血（ICH）和蛛网膜下腔出血（SAH），它们不仅出血部位不同，而且急性和亚急性症状的发病机制也不同。这是一项对数据库的系统综述，旨在寻找过去五年中有关这两种出血性中风理解的研究。六十二篇文章构成了近期文献的直接研究结果，并进一步进行了特征分析，以按事件顺序构建病理生理学。对自发性出血性中风病理生理学的理解之路远未完成。我们的研究结果显示了与脑出血和蛛网膜下腔出血疾病自然史相关的具体且独特的结果，呈现出共同和不同的危险因素、发病时或发病后数天至数周内不同和相似的临床表现，以及两者可能出现的并发症。
