Gastroenterology and Hepatology Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
J Dig Dis. 2021 Mar;22(3):159-166. doi: 10.1111/1751-2980.12975.
To explore the differences in frequency and epidemiology of functional gastrointestinal disorders (FGIDs) in a primary care setting, and to examine the health-related quality of life (HRQOL) and healthcare utilization of FGID patients based on the Rome III and Rome IV criteria.
A cross-sectional study of consecutive adults in a primary healthcare setting was conducted. Differences in epidemiology, and HRQOL of common FGIDs (functional dyspepsia [FD], irritable bowel syndrome [IBS], functional diarrhea, functional constipation [FC]) between the Rome III and IV criteria were explored.
Among a total of 1002 subjects recruited, the frequency of common FGIDs was 20.7% and 20.9% among subjects based on the Rome III and Rome IV criteria, respectively. The frequency of IBS reduced from 4.0% (Rome III) to 0.8% (Rome IV), while that of functional diarrhea increased from 1.2% (Rome III) to 3.3% (Rome IV). In contrast, there was no significant change in the frequency of FD (7.5% [Rome III] vs 7.6% [Rome IV]) and FC (10.5% [Rome III] vs 11.7% [Rome IV]). Most of the Rome III IBS subjects (52.5%, n = 21) who did not meet Rome IV IBS criteria, fulfilled the criteria for FC, functional diarrhea, FD, or overlap syndrome. Subjects with all FGIDs, regardless of criteria, had more healthcare utilization and lower HRQOL compared to non-FGID controls.
The Rome IV criteria alter the frequency of IBS and functional diarrhea, but not FD and FC, when compared to the Rome III criteria. Regardless of criteria, FGIDs had a significant impact on healthcare burden and HRQOL.
探讨初级保健环境中功能性胃肠疾病（FGIDs）的频率和流行病学差异，并根据罗马 III 和罗马 IV 标准检查 FGID 患者的健康相关生活质量（HRQOL）和医疗保健利用情况。
对初级医疗保健环境中的连续成年人进行横断面研究。探讨了罗马 III 和 IV 标准中常见 FGIDs（功能性消化不良 [FD]、肠易激综合征 [IBS]、功能性腹泻、功能性便秘 [FC]）的流行病学和 HRQOL 差异。
在总共招募的 1002 名受试者中，根据罗马 III 和罗马 IV 标准，常见 FGIDs 的频率分别为 20.7%和 20.9%。IBS 的频率从 4.0%（罗马 III）降至 0.8%（罗马 IV），而功能性腹泻的频率从 1.2%（罗马 III）增加到 3.3%（罗马 IV）。相比之下，FD（7.5%[罗马 III]与 7.6%[罗马 IV]）和 FC（10.5%[罗马 III]与 11.7%[罗马 IV]）的频率无显著变化。大多数不符合罗马 IV IBS 标准的罗马 III IBS 受试者（52.5%，n=21）符合 FC、功能性腹泻、FD 或重叠综合征的标准。与非 FGID 对照组相比，无论标准如何，所有 FGIDs 患者的医疗保健利用率更高，HRQOL 更低。
与罗马 III 标准相比，罗马 IV 标准改变了 IBS 和功能性腹泻的频率，但 FD 和 FC 没有改变。无论标准如何，FGIDs 对医疗保健负担和 HRQOL 都有重大影响。
