Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.
Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.
Am J Transplant. 2021 Feb;21 Suppl 2:441-520. doi: 10.1111/ajt.16495.
The number of lung transplants performed continues to increase annually and reached an all-time high in 2019, with decreasing waitlist mortality. These trends are attributable to an increasing number of candidates listed for transplant each year and a continuing increase in the number of donors. Despite these favorable trends, 6.4% of lungs recovered for transplant were not transplanted in 2019, and strategies to optimize use of these available organs may reduce the number of waitlist even further. Time to transplant continued to decrease, as over 50% of candidates waited 3 months or less in 2019, yet regional heterogeneity remained despite policy changes intended to improve allocation equity. Small gains continued in posttransplant survival, with 1-year survival at 88.8%; 3 year, 74.4%; 5 year, 59.2%, and 10 year, 33.1 %.
每年进行的肺移植数量持续增加，2019 年达到历史最高水平，同时候补者死亡率下降。这些趋势归因于每年接受移植的候选人数不断增加，以及供体数量的持续增加。尽管这些趋势良好，但 2019 年仍有 6.4%的可移植肺未进行移植，优化这些可用器官的使用策略可能会进一步减少候补者的数量。移植时间继续缩短，超过 50%的候选者在 2019 年等待 3 个月或更短时间，但尽管有旨在改善分配公平性的政策变化，区域差异仍然存在。移植后存活率继续略有提高，1 年存活率为 88.8%；3 年存活率为 74.4%；5 年存活率为 59.2%，10 年存活率为 33.1%。
