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OPTN/SRTR 2016 年度数据报告:肺。

OPTN/SRTR 2016 Annual Data Report: Lung.

机构信息

Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN.

Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.

出版信息

Am J Transplant. 2018 Jan;18 Suppl 1:363-433. doi: 10.1111/ajt.14562.

Abstract

In 2016, 2692 candidates aged 12 years or older were added to the lung transplant waiting list; 2345 transplants were performed, the largest number of any prior year. The median waiting time for listed candidates in 2016 was 2.5 months, and waiting times were shortest for group D candidates. The transplant rate increased to 191.9 transplants per 100 waitlist years in 2016, with a slight decrease in waitlist mortality to 15.1 deaths per 100 waitlist years. Short-term survival continued to improve, with a 6-month death rate of 6.6% and a 1-year death rate of 10.8% among recipients in 2015 compared with 8.0% and 13.3%, respectively, among recipients in 2014. Long-term survival rates remained unchanged; 55.6% of recipients were alive at 5 years. In 2016, 23 new candidates aged 0-11 years were added to the waiting list and 16 lung transplants were performed. Incidence of posttransplant mortality for lung transplant recipients aged 0-11 years who underwent transplant in 2014-2015 was 13.8% at 6 months and 19.6% at 1 year. Changes in waitlist and transplant demographic features continued to evolve following implementation of the revised lung allocation score in 2015. Some early trends that may be attributable to the revised LAS are shorter waiting times, stabilization of the number of group D candidates listed for transplant, and convergence of LAS with lower prevalence of extremely high scores.

摘要

2016 年,有 2692 名 12 岁及以上的候选者被添加到肺移植等候名单中;共完成 2345 例肺移植手术,这是历年来数量最多的一次。2016 年,等候名单上候选者的中位等候时间为 2.5 个月,D 组候选者的等候时间最短。2016 年,移植率上升至每 100 个等候年限 191.9 例移植,等候名单死亡率略有下降至每 100 个等候年限 15.1 例死亡。短期存活率继续提高,2015 年接受移植者的 6 个月死亡率为 6.6%,1 年死亡率为 10.8%,而 2014 年接受移植者的相应死亡率分别为 8.0%和 13.3%。长期存活率保持不变;5 年时,55.6%的受者存活。2016 年,有 23 名 0-11 岁的新候选者被添加到等候名单中,进行了 16 例肺移植。2014-2015 年接受移植的 0-11 岁肺移植受者,术后 6 个月的死亡率为 13.8%,1 年时的死亡率为 19.6%。自 2015 年修订肺分配评分实施以来,等候名单和移植人群特征的变化仍在继续演变。一些早期趋势可能归因于修订后的 LAS,包括等待时间缩短、D 组候选者列入移植名单的数量稳定,以及 LAS 与较低的极高评分流行率趋同。

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