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临床实践中的共聚焦显微镜检查。

Specular microscopy in clinical practice.

机构信息

Cornea and Anterior Segment Services, LV Prasad Eye Institute, Hyderabad, Telangana, India.

Cornea, Cataract and Refractive Surgery Service, RP Centre, AIIMS, New Delhi, India.

出版信息

Indian J Ophthalmol. 2021 Mar;69(3):517-524. doi: 10.4103/ijo.IJO_574_20.

DOI:10.4103/ijo.IJO_574_20
PMID:33595465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7942069/
Abstract

Specular microscopy is a noninvasive diagnostic tool that allows for in vivo evaluation of corneal endothelium in health and various diseased states. Endothelial imaging helps in the diagnosis and management of several endothelial disorders. The review focuses on the principles of specular microscopy, limitations of endothelial imaging, and its interpretation in common conditions seen in the clinical practice. A thorough PubMed search was done using the keywords specular microscopy, corneal endothelium, and endothelial imaging.

摘要

共聚焦显微镜是一种非侵入性的诊断工具，可用于在体内评估健康和各种病变状态下的角膜内皮。内皮成像有助于诊断和治疗几种内皮疾病。本文综述了共焦显微镜的原理、内皮成像的局限性及其在临床常见疾病中的解读。使用关键词共焦显微镜、角膜内皮和内皮成像，对 PubMed 进行了全面检索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/6478ce62688b/IJO-69-517-g014.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/a637cfa6eb47/IJO-69-517-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/34fda36ae40f/IJO-69-517-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/fba397902f30/IJO-69-517-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/05351e3d5591/IJO-69-517-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/50ecc3fd4e4c/IJO-69-517-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/0301da070d62/IJO-69-517-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/18b7f59571b4/IJO-69-517-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/95827cacabf4/IJO-69-517-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/6478ce62688b/IJO-69-517-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/3b096756f7de/IJO-69-517-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/60b360d3ccd4/IJO-69-517-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/38b2380cd1e3/IJO-69-517-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/a637cfa6eb47/IJO-69-517-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/34fda36ae40f/IJO-69-517-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/fba397902f30/IJO-69-517-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/05351e3d5591/IJO-69-517-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/50ecc3fd4e4c/IJO-69-517-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/0301da070d62/IJO-69-517-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/18b7f59571b4/IJO-69-517-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/95827cacabf4/IJO-69-517-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca72/7942069/6478ce62688b/IJO-69-517-g014.jpg

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Cornea. 2020 Jul;39(7):924-929. doi: 10.1097/ICO.0000000000002277.
2
Corneal endothelium in unilateral Fuchs heterochromic iridocyclitis.单侧Fuchs异色性虹膜睫状体炎中的角膜内皮
Indian J Ophthalmol. 2020 Mar;68(3):447-449. doi: 10.4103/ijo.IJO_869_19.
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The effects of diabetes mellitus on the corneal endothelium: A review.糖尿病对角膜内皮的影响：综述。
评估初治眼玻璃体内注射抗血管内皮生长因子（Anti-VEGF）后短期角膜内皮的改变。
Rom J Ophthalmol. 2025 Apr-Jun;69(2):212-218. doi: 10.22336/rjo.2025.34.
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The Immediate Effects of Different Types of Tea Consumption on Ocular Biometric and Specular Microscopic Parameters in Healthy Subjects.不同类型茶饮对健康受试者眼部生物特征及镜面显微镜参数的即时影响
Eurasian J Med. 2025 Apr 7;57(1):1-5. doi: 10.5152/eurasianjmed.2025.24589.
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Corneal endothelial and retinal microvascular changes in pseudoexfoliation syndrome: insights from specular microscopy and OCT angiography.假性剥脱综合征中的角膜内皮和视网膜微血管变化：来自镜面显微镜检查和光学相干断层扫描血管造影的见解
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Am J Ophthalmol Case Rep. 2024 Jul 31;36:102136. doi: 10.1016/j.ajoc.2024.102136. eCollection 2024 Dec.
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