Khan Waheed Ullah, Qin Liying, Alam Abid, Zhou Ping, Peng Yong, Wang Yuhua
National and Local Joint Engineering Laboratory of Optical-Conversion Materials and Technology & School of Physical Science and Technology, Lanzhou University, Lanzhou 730000, P.R. China.
School of Stomotology, Lanzhou University, Lanzhou 730000, P.R. China.
Nanoscale. 2021 Feb 25;13(7):4301-4307. doi: 10.1039/d0nr09131f.
High stability and water solubility of fluorescent nanomaterials are considered key factors to evaluate their feasibility for fundamental applications. Herein, water-soluble and thermally stable, green-emitting carbon nanodots (CNDs) have been synthesized via a facile hydrothermal method with an average size of 1.9 nm. CNDs showed green emission centered at 544 nm with the photo-luminescence quantum yield (PLQY) of up to 10.1% under the excitation of 400 nm. The obtained CNDs demonstrated high resistance towards photo-bleaching and an ionic (KCl) environment. Moreover, the aqueous solution of CNDs exhibited excellent stability under harsh thermal conditions from 10 °C to 80 °C. The as-prepared CNDs showed stable performance at high temperatures, even after keeping them at 80 °C for 30 min. Furthermore, the green emissive CNDs were incubated in T-ca cancer cells for bio-imaging applications. The results indicated that CNDs can served as an effective thermally-stable bio-imaging agent in T-ca cells at the physiological temperature range of 25 °C-45 °C. Green emission and excellent thermal stability make these CNDs promising fluorescent materials for potential applications in the medical field, which requires long-wavelength fluorescence and high-temperature imaging.
荧光纳米材料的高稳定性和水溶性被认为是评估其基础应用可行性的关键因素。在此，通过简便的水热法合成了水溶性且热稳定的绿色发光碳纳米点（CNDs），其平均尺寸为1.9纳米。在400纳米激发下，CNDs在544纳米处呈现绿色发射，光致发光量子产率（PLQY）高达10.1%。所获得的CNDs对光漂白和离子（KCl）环境表现出高抗性。此外，CNDs的水溶液在10℃至80℃的苛刻热条件下表现出优异的稳定性。制备的CNDs在高温下表现出稳定的性能，即使在80℃保持30分钟后也是如此。此外，将绿色发光的CNDs在T-ca癌细胞中孵育用于生物成像应用。结果表明，在25℃至45℃的生理温度范围内，CNDs可作为T-ca细胞中有效的热稳定生物成像剂。绿色发射和优异的热稳定性使这些CNDs成为医学领域潜在应用中有前景的荧光材料，医学领域需要长波长荧光和高温成像。
