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成人 HIV 感染者共病的综述:科学现状。

A Review of Chronic Comorbidities in Adults Living With HIV: State of the Science.

机构信息

Allison R. Webel, PhD, RN, FAAN, is Associate Professor of Nursing, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA, and Associate Editor, Journal of the Association of Nurses in AIDS Care .

Julie Schexnayder, DNP, MPH, ACNP-BC, is a PhD Candidate, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.

出版信息

J Assoc Nurses AIDS Care. 2021;32(3):322-346. doi: 10.1097/JNC.0000000000000240.


DOI:10.1097/JNC.0000000000000240
PMID:33595986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8815414/
Abstract

People living with HIV are living longer, high-quality lives; however, as they age, this population is at increased risk for developing chronic comorbidities, including cardiovascular disease, certain types of cancer (e.g., lung, anal, and liver), and diabetes mellitus. The purpose of this state-of-the-science review is to provide an evidence-based summary on common physical comorbidities experienced by people living and aging with HIV. We focus on those chronic conditions that are prevalent and growing and share behavioral risk factors that are common in people living with HIV. We will discuss the current evidence on the epidemiology, physiology, prevention strategies, screening, and treatment options for people living with HIV across resource settings.

摘要

HIV 感染者的寿命正在延长,生活质量也在提高;然而,随着年龄的增长,这一人群罹患慢性合并症的风险增加,包括心血管疾病、某些类型的癌症(例如肺癌、肛门癌和肝癌)以及糖尿病。本现状综述的目的是提供有关 HIV 感染者的常见身体合并症的循证总结。我们重点介绍那些在 HIV 感染者中普遍存在且不断增加的慢性疾病,并共同探讨与 HIV 感染者常见的行为危险因素。我们将讨论资源环境下 HIV 感染者的流行病学、生理学、预防策略、筛查和治疗选择的现有证据。

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本文引用的文献

[1]
Chronic Obstructive Pulmonary Disease.

Ann Intern Med. 2020-8-4

[2]
Deaths Attributable to Cancer in the US Human Immunodeficiency Virus Population During 2001-2015.

Clin Infect Dis. 2021-5-4

[3]
Risk of Anal High-grade Squamous Intraepithelial Lesions Among Renal Transplant Recipients Compared With Immunocompetent Controls.

Clin Infect Dis. 2021-7-1

[4]
Epidemiology of Hepatocellular Carcinoma.

Hepatology. 2021-1

[5]
Association of antiretroviral therapy with anal high-risk human papillomavirus, anal intraepithelial neoplasia, and anal cancer in people living with HIV: a systematic review and meta-analysis.

Lancet HIV. 2020-2-25

[6]
Obesity and Weight Gain in Persons with HIV.

Curr HIV/AIDS Rep. 2020-4

[7]
Incidence of chronic obstructive pulmonary disease in people with HIV in Ontario, 1996-2015: a retrospective population-based cohort study.

CMAJ Open. 2020

[8]
Physical activity trends and metabolic health outcomes in people living with HIV in the US, 2008-2015.

Prog Cardiovasc Dis. 2020-2-12

[9]
Prevention of stroke in people living with HIV.

Prog Cardiovasc Dis. 2020-1-31

[10]
AGA Clinical Practice Update on Screening and Surveillance for Hepatocellular Carcinoma in Patients With Nonalcoholic Fatty Liver Disease: Expert Review.

Gastroenterology. 2020-1-30

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