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赌博障碍的非药物治疗:随机对照试验的系统评价。

Non-pharmacological treatment of gambling disorder: a systematic review of randomized controlled trials.

机构信息

School of Medicine, University of Minho, Braga, Portugal.

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal.

出版信息

BMC Psychiatry. 2021 Feb 17;21(1):105. doi: 10.1186/s12888-021-03097-2.

Abstract

BACKGROUND

The main focus of the non-pharmacological treatment of Gambling Disorder (GD) is the behaviour, cognition and motivation of the patient, addressing the psychological determinants of gambling. Although there is not a gold standard non-pharmacological treatment yet, many studies already had promising results, and the outcomes were even better when pharmacotherapies were combined with psychotherapies. This review intended to synthesise the efficacy of various available non-pharmacological therapies for GD evaluated in randomized controlled trials.

METHODS

A systematic search was conducted in PubMed and in Cochrane Library for randomized controlled trials. Studies were included if participants had GD as their primary diagnosis and excluded if patients had other comorbidities.

RESULTS

From 320 records identified, 22 studies were included in the critical appraisal. They included a total of 1694 patients, with a mean age of 42.94 years, and a 62.31% of males. Seven trials revealed the efficacy of cognitive behaviour therapy in improving significantly the outcomes. Three studies assessing cognitive therapy showed significant improvements in gambling symptoms, while one study showed improvements in gambling behaviour using exposure therapy. Combined or separate motivational interviewing and imaginal desensitization had significant results in 4 trials. Four other studies also showed efficacy for: couples therapy, node-link mapping therapy, 12-step facilitated and personalized feedback intervention. Physical exercise had promising results but did not reach significance.

CONCLUSION

The literature included in this review showed the heterogeneity of available psychotherapies. The majority of studies supported the efficacy of the tested therapies, while some of them, due to limitations such as small sample sizes or inadequate control groups, failed to reach significance.

摘要

背景

赌博障碍(GD)非药物治疗的主要重点是患者的行为、认知和动机,针对赌博的心理决定因素。尽管还没有一种标准的非药物治疗方法,但许多研究已经取得了有希望的结果,当药物治疗与心理治疗相结合时,结果甚至更好。本综述旨在综合评估各种已发表的随机对照试验中用于 GD 的可用非药物治疗方法的疗效。

方法

在 PubMed 和 Cochrane Library 中进行了系统检索,以寻找随机对照试验。如果参与者的主要诊断为 GD,则纳入研究;如果患者有其他合并症,则排除研究。

结果

从 320 条记录中,有 22 项研究被纳入批判性评价。它们共纳入了 1694 名患者,平均年龄为 42.94 岁,男性占 62.31%。有 7 项试验表明认知行为疗法在改善结果方面具有显著效果。三项评估认知疗法的研究显示出赌博症状的显著改善,而一项使用暴露疗法的研究显示出赌博行为的改善。结合或单独的动机性访谈和想象脱敏在 4 项试验中具有显著效果。另外 4 项研究也表明:夫妻治疗、节点链接映射治疗、12 步促进和个性化反馈干预具有疗效。体育锻炼也显示出了有希望的结果,但没有达到显著性。

结论

本综述中纳入的文献显示了可用心理治疗方法的异质性。大多数研究支持所测试疗法的疗效,而有些研究由于样本量小或对照不足等限制,未能达到显著性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3b/7888125/28a6c0526909/12888_2021_3097_Fig1_HTML.jpg

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