婴儿体脂与经口喂养结局：一项初步研究。
Body adiposity and oral feeding outcomes in infants: a pilot study.
机构信息
Division of Neonatology, Department of Pediatrics, Nemours Children's Hospital, University of Central Florida College of Medicine, Orlando, FL, USA.
Innovative Infant Feeding Disorders Research Program, Nationwide Children's Hospital, Columbus, OH, USA.
出版信息
J Perinatol. 2021 May;41(5):1059-1064. doi: 10.1038/s41372-021-00975-1. Epub 2021 Feb 17.
BACKGROUND
Prevalence of oral feeding difficulties in high-risk infants is increasing. Desire to take orally can be influenced by hunger and satiety, which may influence growth and body fat.
OBJECTIVE
To determine the association between body adiposity and infant oral feeding.
METHODS
Retrospective case-control study of infants ≥37-week postmenstrual age (PMA). Infants on tube feeding (cases) compared to birth gestation-matched infants on full oral feeding (controls). Body composition was determined by air displacement plethysmography.
RESULTS
Overall, 16 cases vs. 16 controls. At study, cases vs. controls had similar PMA, weight and length z-scores, and calorie intake. The mean oral intake was significantly less in cases vs. controls (66 vs. 168 ml/kg/day, p < 0.001). Cases had significantly higher percentage of fat mass (18.7 vs. 10.9) and fat-mass z-score (1.62 vs. 0.08) (p < 0.05), but similar fat-free mass vs. controls. Five case infants required gastrostomy.
CONCLUSIONS
Higher body adiposity may worsen the infant oral feeding outcomes.
背景
高危婴儿的经口喂养困难发生率正在增加。摄食意愿可能受到饥饿和饱腹感的影响，而这可能会影响生长和体脂肪。
目的
确定婴儿体脂肪与经口喂养之间的关系。
方法
对胎龄≥37 周的婴儿进行回顾性病例对照研究。将接受管饲喂养的婴儿（病例组）与接受完全经口喂养且胎龄匹配的婴儿（对照组）进行比较。通过空气置换体积描记法来确定身体成分。
结果
共纳入 16 例病例组和 16 例对照组。在研究时，病例组与对照组的胎龄校正后体重和身长 Z 评分以及热量摄入相似。病例组的经口摄入量明显少于对照组（66 比 168ml/kg/天，p<0.001）。病例组的体脂肪百分比（18.7 比 10.9）和体脂肪质量 Z 评分（1.62 比 0.08）明显更高（p<0.05），但与对照组的去脂体重相似。5 例病例组婴儿需要进行胃造口术。
结论
较高的体脂肪量可能会使婴儿的经口喂养结果恶化。
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