Daly-Wolfe Kelly M, Jordan Kristine C, Slater Hillarie, Beachy Joanna C, Moyer-Mileur Laurie J
1] Department of Pediatrics, University of Utah, Salt Lake City, Utah [2] Division of Nutrition, University of Utah, Salt Lake City, Utah.
Department of Pediatrics, University of Utah, Salt Lake City, Utah.
Pediatr Res. 2015 Sep;78(3):336-41. doi: 10.1038/pr.2015.103. Epub 2015 May 28.
Premature birth is associated with increased adipose deposition after birth. Standard anthropometry (body weight, length, and head circumference) may not adequately assess fat deposition. Validated methods to assess adiposity are needed to optimize growth quality in preterm infants. The purpose of this study was to identify covariates of infant body fat.
Air displacement plethysmography (ADP), standard anthropometry, and body circumferences were measured at hospital discharge in preterm (n = 28; 31-35 wk postmenstrual age (PMA)) and term (n = 28; 38-41 wks PMA) infants.
Body weight, length, and head circumference were lower for preterm infants (P < 0.05) at hospital discharge compared with that of term infants. Despite smaller body size and younger PMA, preterm infant percent body fat (%BF) by ADP was 12.33 ± 4.15% vs. 9.64 ± 4.01% in term infants (P = 0.01). Mid-arm circumference (MAC) is a covariate of %BF in both preterm and term infants (adjusted R(2) = 0.49; P < 0.001). In preterm infants alone, MAC accounted for 60.4% of the variability of percent body fat (%BF) by ADP (P < 0.01).
Preterm infants have increased body fat deposition as they approach term-corrected age, and MAC is a reliable, low-cost measure for monitoring infant body fat deposition in preterm and term infants.
早产与出生后脂肪沉积增加有关。标准人体测量法（体重、身长和头围）可能无法充分评估脂肪沉积情况。需要有效的方法来评估肥胖程度，以优化早产儿的生长质量。本研究的目的是确定婴儿体脂的协变量。
在出院时，对早产（n = 28；孕龄31 - 35周）和足月（n = 28；孕龄38 - 41周）婴儿进行空气置换体积描记法（ADP）测量、标准人体测量及身体周长测量。
出院时，早产儿的体重、身长和头围低于足月儿（P < 0.05）。尽管早产儿体型较小且孕龄较小，但通过ADP测量的早产儿体脂百分比（%BF）为12.33 ± 4.15%，而足月儿为9.64 ± 4.01%（P = 0.01）。在早产儿和足月儿中，上臂围（MAC）都是%BF的协变量（调整后R² = 0.49；P < 0.001）。仅在早产儿中，MAC占ADP测量的体脂百分比（%BF）变异性的60.4%（P < 0.01）。
随着接近足月校正年龄，早产儿的体脂沉积增加；并且MAC是监测早产儿和足月儿体脂沉积的一种可靠、低成本的测量方法。
