Anastassiadou Maria, Bernasconi Giovanni, Brancato Alba, Carrasco Cabrera Luis, Ferreira Lucien, Greco Luna, Jarrah Samira, Kazocina Aija, Leuschner Renata, Magrans Jose Oriol, Miron Ileana, Nave Stefanie, Pedersen Ragnor, Reich Hermine, Rojas Alejandro, Sacchi Angela, Santos Miguel, Scarlato Alessia Pia, Theobald Anne, Vagenende Benedicte, Verani Alessia
EFSA J. 2021 Feb 5;19(2):e06405. doi: 10.2903/j.efsa.2021.6405. eCollection 2021 Feb.
The applicant Syngenta Crop Protection AG submitted a request to the competent national authority in Finland to evaluate the confirmatory data that were identified for propiconazole in the framework of the MRL review under Article 12 of Regulation (EC) No 396/2005 as not available. Following the decision on the non-renewal of the approval of propiconazole and the decision to lower the maximum residue levels (MRLs) for propiconazole to the limit of quantification (LOQ) for all commodities, the data gaps identified in the MRL review are no longer relevant. EFSA summarised some new studies on the toxicological profile of propiconazole metabolites CGA91305, SYN547889 and NOA436613, which were assessed by the rapporteur Member State. Overall, the available information is not sufficient to characterise the toxicological profile of metabolites convertible to 2,4-dichlorobenzoic acid as data gaps still exist for SYN547889, NOA436613, CGA118244, CGA118245, CGA91304 and CGA91305.
申请人先正达作物保护股份公司向芬兰国家主管当局提交了一项请求，要求评估在第（EC）No 396/2005号法规第12条规定的最大残留限量（MRL）审查框架下确定的丙环唑的确认数据，因为这些数据不可用。在关于不续批丙环唑的决定以及将丙环唑在所有商品中的最大残留限量（MRL）降至定量限（LOQ）的决定之后，MRL审查中确定的数据缺口不再相关。欧洲食品安全局（EFSA）总结了一些关于丙环唑代谢物CGA91305、SYN547889和NOA436613毒理学概况的新研究，这些研究由报告成员国进行了评估。总体而言，现有信息不足以描述可转化为2,4-二氯苯甲酸的代谢物的毒理学概况，因为SYN547889、NOA436613、CGA118244、CGA118245、CGA91304和CGA91305的数据缺口仍然存在。
