Sankara Paté, Djiguimde Windinmanégdé Pierre, Ahnoux-Zabsonre Ahgbatouhabéba, Sanou Jérôme, Meda-Hien Gertrude, Diomande Ibrahim Abib, Dolo-Traore Mariam, Diallo Jean Wenceslas, Bouda Gabrielle Chantal, Sidibe Gaoussou
Centre National de Lutte contre la Cécité, Ministère de la Santé, Ouagadougou, Burkina Faso.
Service d´Ophtalmologie, Centre Hospitalier Universitaire de Bogodogo, Ouagadougou, Burkina Faso.
Pan Afr Med J. 2020 Nov 25;37:269. doi: 10.11604/pamj.2020.37.269.20556. eCollection 2020.
Retinoblastoma is the most common intraocular cancer of childhood. Its estimated incidence is 1 case per 15 000 to 18 000 births. The purpose of this study is to highlight the epidemiological and clinical features of this disease as well as its management in Burkina Faso. We conducted a retrospective study over a period of 5 years at the Yalgado Ouedraogo University Hospital Center. The average age of patients was 33 months, with predominance of male sex (68.75%). Exophthalmia was the most frequent reason for consultation (59.37%). The predominant pattern was unilateral (75%) associated with eye protrusion (59.38%). Chemotherapy associated with surgery was the treatment of choice, with a 5-year survival rate of 34.37%. Retinoblastoma is one of the most common cancers in children younger than 5 years. In our low-income country this disease is diagnosed late. Patients´ management is complex and is commonly associated with poor prognosis. Mortality and morbidity from this disease are disproportionate in our country facing a shortage of technical equipment. In our low-income country, patient´s management should be based on early detection of the disease as well as on adequate treatment.
视网膜母细胞瘤是儿童期最常见的眼内癌。其估计发病率为每15000至18000例出生中有1例。本研究的目的是突出该疾病在布基纳法索的流行病学和临床特征及其治疗情况。我们在亚尔加杜·韦德拉奥果大学医院中心进行了一项为期5年的回顾性研究。患者的平均年龄为33个月，男性占主导（68.75%）。眼球突出是最常见的就诊原因（59.37%）。主要模式为单侧（75%）并伴有眼球突出（59.38%）。化疗联合手术是首选治疗方法，5年生存率为34.37%。视网膜母细胞瘤是5岁以下儿童中最常见的癌症之一。在我们这个低收入国家，这种疾病诊断较晚。患者的治疗很复杂，且通常预后不佳。在我们国家，由于技术设备短缺，这种疾病导致的死亡率和发病率不成比例。在我们这个低收入国家，患者的治疗应基于疾病的早期发现以及适当的治疗。
