Rahman M, Harrington M, Stott M A, Li Y, Sampad M J N, Yuzvinsky T D, Hawkins A R, Schmidt H
School of Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.
ECEn Department, Brigham Young University, 450 Engineering Building, Provo, Utah 84602, USA.
Optica. 2019 Sep 20;6(9):1130-1131. doi: 10.1364/optica.6.001130. Epub 2019 Aug 28.
We use optical trapping to deliver molecular targets to the vicinity of a nanopore for high-throughput single molecule analysis on an optofluidic chip. DNA detection rates increase over 80× to enable detection at attomolar concentrations.
我们利用光镊将分子靶标递送至纳米孔附近,以在光流体芯片上进行高通量单分子分析。DNA检测速率提高了80多倍,能够在阿托摩尔浓度下进行检测。