Kulkarni Varun, Uttamani Juhi Raju, Asar Neset Volkan, Nares Salvador, Tözüm Tolga Fikret
Int J Oral Maxillofac Implants. 2021 Jan-Feb;36(1):59-67. doi: 10.11607/jomi.8541.
Short dental implants serve as a valuable alternative for patients with limited bone height. Immediate or early provisionalization facilitates a more physiologic environment for the gingival tissues to be modeled. The purpose of this meta-analysis was to systematically review and evaluate the implant survival and marginal bone loss with immediate and early loading protocols of short dental implants (≤ 6 mm).
A literature search (electronic and manual) was conducted to identify studies with a focused PICO question: "In patients with short dental implants, does loading time affect treatment outcomes?" Studies using an immediate or early loading protocol for restoration of short implants with a mean follow-up of at least 1 year, and refraining from the use of advanced surgical procedures (sinus floor elevation, bone augmentation), were included. After evaluating patient selection and outcome reporting biases, a meta-analysis was conducted to assess implant survival and bone loss for studies fulfilling the inclusion criteria. Bone loss differences between immediate and early loading protocols were evaluated by Student t test, and Spearman correlation analysis was used to analyze the trends between crown-to-implant (C/I) ratio and bone loss.
A total of 396 studies with patients receiving short implants (≤ 6 mm) with immediate or early prosthetic loading protocols were identified. For the 7 included studies, the pooled implant survival rate for 322 implants with a follow-up ranging from 1 to 10 years (5 years) was 91.63% (95% CI: 88% to 94%), with a mean bone loss effect estimate of 0.52 ± 0.1 mm (z = 3.07, P < .002). The differences observed in the mean bone loss for studies using immediate loading as opposed to early loading were not statistically significant. A moderate but significant positive correlation was observed between the C/I ratio and mean bone loss levels (r = 0.67, P = .02).
Short implants with immediate or early loading protocols have satisfactory long-term treatment prospects with satisfactory implant survival rates and minimal bone loss.
短牙种植体为骨高度受限的患者提供了一种有价值的替代方案。即刻或早期临时修复有助于为牙龈组织塑造更接近生理状态的环境。本荟萃分析的目的是系统评价和评估短牙种植体(≤6mm)即刻和早期加载方案的种植体存留率和边缘骨吸收情况。
进行文献检索(电子检索和手工检索),以确定聚焦于PICO问题的研究:“在短牙种植体患者中,加载时间是否会影响治疗效果?”纳入使用即刻或早期加载方案修复短种植体且平均随访至少1年、未采用高级外科手术(上颌窦底提升、骨增量)的研究。在评估患者选择和结果报告偏倚后,对符合纳入标准的研究进行荟萃分析,以评估种植体存留率和骨吸收情况。通过Student t检验评估即刻加载和早期加载方案之间的骨吸收差异,并使用Spearman相关分析分析冠根比(C/I)与骨吸收之间的趋势。
共识别出396项关于接受短种植体(≤6mm)即刻或早期修复加载方案患者的研究。对于纳入的7项研究,322颗种植体随访1至10年(平均5年)的合并种植体存留率为91.63%(95%CI:88%至94%),平均骨吸收效应估计值为0.52±0.1mm(z = 3.07,P <.002)。与早期加载相比,即刻加载研究中观察到的平均骨吸收差异无统计学意义。C/I比与平均骨吸收水平之间存在中度但显著的正相关(r = 0.67,P =.02)。
采用即刻或早期加载方案的短种植体具有令人满意的长期治疗前景,种植体存留率令人满意,骨吸收极少。