Wamaket N, Dieng H, Komalamisra N, Apiwathnasorn C, Morales R E, Thanomsub B W, Srisawat R, Attrapadung S
Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University, 420/6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand.
Institute of Biodiversity and Environmental Conservation, Universiti Malaysia Sarawak 94300, Kota Samarahan, Sarawak, Malaysia.
Trop Biomed. 2018 Sep 1;35(3):610-618.
Plants contain numerous bioactive compounds that can be used to develop environmentally-safe insect control agents. Castor oil is a vegetable oil derived from the seeds of castor bean and is widely used as an industrial lubricant and medicinal purgative. In search of an alternative natural insecticide, the objective of this study was to evaluate the larvicidal and adulticidal activities of castor oil against the important dengue vector, Ae. aegypti. Larvicidal and adulticidal bioassays were conducted following the World Health Organization methods. Larvicidal activity was observed at castor oil concentrations of 10, 25, 50, 75, and 100 ppm; larval mortality was checked after 48 h of exposure and the lethal concentration (LC) at LC and LC were 51.38 and 116.26 ppm, respectively. Adulticidal activity was determined by topical application at the concentrations of 1, 5, 10, 15, and 20 µg/ mg on female mosquitoes and the mortality was checked after 24 h of exposure. The effective adulticidal activity was apparent with the LD and LD values of 6.03 and 25.07 µg/mg against female mosquitoes. The results indicated that castor oil has potential in the practical control of both immature and adult stages of the mosquito vector.
植物含有多种生物活性化合物,可用于开发对环境安全的杀虫剂。蓖麻油是一种从蓖麻籽中提取的植物油,广泛用作工业润滑剂和药用泻药。为了寻找一种替代天然杀虫剂,本研究的目的是评估蓖麻油对重要登革热媒介埃及伊蚊的杀幼虫和杀成虫活性。按照世界卫生组织的方法进行了杀幼虫和杀成虫生物测定。在蓖麻油浓度为10、25、50、75和100 ppm时观察到杀幼虫活性;暴露48小时后检查幼虫死亡率,LC和LC时的致死浓度(LC)分别为51.38和116.26 ppm。通过对雌蚊以1、5、10、15和20 µg/ mg的浓度进行局部涂抹来测定杀成虫活性,暴露24小时后检查死亡率。对雌蚊的LD和LD值分别为6.03和25.07 µg/mg时,有效杀成虫活性明显。结果表明,蓖麻油在实际控制蚊虫媒介的幼虫和成虫阶段具有潜力。