Department of Urology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences, Sina Hospital, Tehran, Iran.
Urologia. 2021 Aug;88(3):185-189. doi: 10.1177/0391560321993540. Epub 2021 Feb 18.
It is assumed that the outcome of kidney transplantation from living donors is more favorable than deceased donors. However, over the years there has been an overall improvement in transplant survival from both living and deceased donors. In this article we have evaluated and compared the most recent results in living and deceased donor kidney transplantations.
Four hundred and forty six patients underwent kidney transplantation in our center from September 2009 to March 2014. The patients divided in two groups living (group A) and deceased (group B) donor transplantation groups. The patients were followed until September 2016. Acute rejection, graft survival, delayed graft function, renal artery thrombosis, graft nephrectomy, ureterocutaneous fistula, postoperative hypertension, mortality, hospital stay, hyperlipidemia, post transplantation diabetes and lymphocele rate measured and compared in two groups.
Most variables were not different between the two groups except lymphocele and delayed graft function. Lymphocele was more prevalent in group A (13.8% vs 3.1%, -value = 0.02) and delayed graft function results were more desirable in living donor transplantation group (group B).
Although, delayed graft function was less common in transplantation from living donors, short, and long term graft survival was not significantly different in this study.
人们认为，活体供者的肾移植结果比已故供者更有利。然而，近年来，无论是活体供者还是已故供者的移植存活率都有了整体提高。在本文中，我们评估并比较了活体和已故供者肾移植的最新结果。
我们中心有 446 例患者于 2009 年 9 月至 2014 年 3 月期间接受了肾移植。这些患者被分为两组：活体（A 组）和已故（B 组）供者移植组。这些患者随访至 2016 年 9 月。我们对两组患者的急性排斥反应、移植物存活率、延迟移植物功能、肾动脉血栓形成、移植肾切除术、输尿管皮肤瘘、术后高血压、死亡率、住院时间、高脂血症、移植后糖尿病和淋巴囊肿发生率进行了测量和比较。
除了淋巴囊肿和延迟移植物功能外，两组间大多数变量无差异。A 组淋巴囊肿更常见（13.8% vs 3.1%，-值=0.02），且 B 组活体供者移植组延迟移植物功能结果更好。
尽管活体供者的移植中延迟移植物功能不太常见，但在这项研究中，短期和长期移植物存活率无显著差异。
