Igwesi-Chidobe Chinonso N, Emmanuel Grace Nneoma, Okezue Obinna Chinedu
Medical Rehabilitation, University of Nigeria, Enugu, Enugu, Nigeria
Medical Rehabilitation, University of Nigeria, Enugu, Enugu, Nigeria.
BMJ Open. 2021 Feb 18;11(2):e042107. doi: 10.1136/bmjopen-2020-042107.
Twenty five per cent of pregnant women with musculoskeletal pain have disabling symptoms that negatively influence quality of life. Studies have reported varying effects of non-pharmacological interventions including exercise, manipulation and pelvic belts for pregnant women with musculoskeletal problems. The overall effectiveness and acceptability of these interventions is uncertain due to lack of synthesised evidence. This protocol is for the first systematic review of community-based non-pharmacological interventions for improving pain, disability and quality of life in pregnant women with musculoskeletal conditions from studies published until August 2020.
A detailed search of PubMed, CINAHL, CENTRAL, Global Index Medicus, African Index Medicus, African Journal Online, Western Pacific Region Index Medicus, Latin American and Caribbean Centre on Health Science Information, Index Medicus for South-East Asia Region, IRIS (WHO digital publications), British Library for Development Studies and Google Scholar. Additional studies will be located from the reference list of identified studies and relevant systematic reviews. The databases will be searched from inception to August 2020. Appraisal of study quality will be performed with the Mixed Methods Appraisal Tool. Data will be synthesised using a mixed-studies synthesis design-the convergent synthesis. The description of interventions in all study designs will be summarised narratively. Meta-analyses will be used to statistically summarise the effectiveness of interventions in randomised controlled trials and the factors that influence these. Other quantitative studies will be summarised narratively to answer the objectives. Thematic synthesis will be used to summarise results of qualitative studies. The outcomes of interest include pain, disability and quality of life. This paper is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols 2015 guidelines.
Ethical clearance is not required. Findings will be presented at conferences and published in peer-reviewed journals.
CRD42020189535.
25%患有肌肉骨骼疼痛的孕妇出现了致残症状，对生活质量产生了负面影响。研究报告了包括运动、手法治疗和骨盆带在内的非药物干预措施对患有肌肉骨骼问题的孕妇的不同影响。由于缺乏综合证据，这些干预措施的总体有效性和可接受性尚不确定。本方案是对截至2020年8月发表的研究中，基于社区的非药物干预措施改善患有肌肉骨骼疾病的孕妇疼痛、残疾和生活质量的首次系统评价。
对PubMed、CINAHL、CENTRAL、全球医学索引、非洲医学索引、非洲期刊在线、西太平洋地区医学索引、拉丁美洲和加勒比卫生科学信息中心、东南亚地区医学索引、IRIS（世界卫生组织数字出版物）、英国发展研究图书馆和谷歌学术进行详细检索。将从已识别研究的参考文献列表和相关系统评价中查找其他研究。数据库将从创建到2020年8月进行检索。将使用混合方法评估工具对研究质量进行评估。将使用混合研究综合设计——收敛综合来综合数据。将对所有研究设计中的干预措施描述进行叙述性总结。荟萃分析将用于统计总结随机对照试验中干预措施的有效性以及影响这些有效性的因素。其他定量研究将进行叙述性总结以回答研究目的。将使用主题综合来总结定性研究的结果。感兴趣的结果包括疼痛、残疾和生活质量。本文按照2015年系统评价和荟萃分析方案的首选报告项目指南进行报告。
无需伦理批准。研究结果将在会议上展示并发表在同行评审期刊上。
PROSPERO注册号：CRD42020189535。
