Alonso-Matielo Heloísa, da Silva Oliveira Victória Regina, de Oliveira Victhor Teixeira, Dale Camila Squarzoni
Department of Anatomy, Laboratory of Neuromodulation and Experimental Pain, University of São Paulo, São Paulo, Brazil.
Front Physiol. 2021 Feb 2;12:624154. doi: 10.3389/fphys.2021.624154. eCollection 2021.
The COVID19 pandemic has impacted the lives and health of persons worldwide and although majority of COVID19 patients present with respiratory symptoms, pain emerges as an important feature of COVID19 infection. About 15-20% of patients progress to a severe condition that requires hospitalization. Although the disease was initially reported as a respiratory syndrome, other systems such as cardiovascular, renal, and nervous systems may be affected in the acute stages, increasing the need for continuous support to treat multiple sequelae caused by the disease. Due to the severity of the disease, damages found after discharge should also be considered. Providing multidisciplinary interventions promoting physical and psychological recovery in the first stages of hospitalization can minimize these damages. Cognitive, physical and psychological dysfunction reported by COVID19 patients after discharge can have profound effects on quality of life. Pain is usually part of this dysfunction, but it is still poorly understood how it affects survivors of COVID19 infections. There is limited information about the clinical characteristics, treatment and outcome of maintenance of pain in COVID19 patients. The purpose of this narrative review is to provide an overview of the implications of COVID19 on acute and chronic pain states.
新冠疫情影响了全世界人们的生活和健康，尽管大多数新冠患者表现出呼吸道症状，但疼痛已成为新冠感染的一个重要特征。约15%-20%的患者会发展为需要住院治疗的重症。尽管该疾病最初被报告为一种呼吸道综合征，但在急性期，心血管、肾脏和神经系统等其他系统可能会受到影响，这增加了持续支持以治疗该疾病引起的多种后遗症的需求。由于该疾病的严重性，出院后发现的损害也应予以考虑。在住院初期提供促进身体和心理恢复的多学科干预措施可以将这些损害降至最低。新冠患者出院后报告的认知、身体和心理功能障碍会对生活质量产生深远影响。疼痛通常是这种功能障碍的一部分，但人们对其如何影响新冠感染幸存者仍知之甚少。关于新冠患者疼痛的临床特征、治疗和维持结果的信息有限。本叙述性综述的目的是概述新冠对急性和慢性疼痛状态的影响。
