Ubaldo Onion Gerald V, Palo Jose Emmanuel M, Cinco Jude Erric L
Acute and Critical Care Institute, The Medical City-Ortigas, Pasig City 1605, Philippines.
Crit Care Res Pract. 2021 Jan 30;2021:7510306. doi: 10.1155/2021/7510306. eCollection 2021.
On January 30, 2020, the WHO declared the novel coronavirus of 2019 a pandemic, causing millions of cases and thousands of deaths worldwide, exposing the vulnerabilities of healthcare systems around the world with each country having its own experience. These ranged from patient clinical profiles to management recommendations and to government interventions. There is a paucity of published data regarding Philippine experience. This study is a retrospective, descriptive study of ninety-one COVID-19 probable patients admitted in the COVID ICU of The Medical City from March 16 to May 7, 2020. We described clinical and demographic characteristics amongst COVID-19-confirmed and -negative patients. Therapeutic interventions including COVID-19 investigational drug use and other organ failure strategies were noted and tested for association with ICU survivors and nonsurvivors. We observed that there was no therapeutic intervention that was associated with improved outcomes, with some interventions showing trends favoring the ICU nonsurvivor group. These interventions include, but are not limited to, the use of hydroxychloroquine and tocilizumab, and prone positioning. We also observed that a higher SAPS-3 score was associated with the COVID-19 positive group and the ICU nonsurvivor group. On PubMed search, there seems to be no Philippine-specific literature regarding COVID-19 ICU experience. Further investigations to include more variables are recommended.
2020年1月30日，世界卫生组织宣布2019年新型冠状病毒为大流行病，在全球造成数百万病例和数千人死亡，暴露出世界各地医疗系统的脆弱性，每个国家都有自己的经历。这些经历涵盖了患者的临床特征、管理建议以及政府干预措施。关于菲律宾的经验，已发表的数据很少。本研究是一项回顾性描述性研究，研究对象为2020年3月16日至5月7日在医疗城新冠重症监护病房收治的91例疑似新冠患者。我们描述了新冠确诊患者和阴性患者的临床和人口统计学特征。记录了包括使用新冠研究药物和其他器官衰竭治疗策略在内的治疗干预措施，并对其与重症监护病房幸存者和非幸存者的相关性进行了测试。我们观察到，没有任何治疗干预措施与改善预后相关，有些干预措施显示出有利于重症监护病房非幸存者组的趋势。这些干预措施包括但不限于使用羟氯喹和托珠单抗，以及俯卧位通气。我们还观察到，较高的序贯器官衰竭评估（SAPS-3）评分与新冠阳性组和重症监护病房非幸存者组相关。在PubMed数据库搜索中，似乎没有关于菲律宾新冠重症监护病房经验的特定文献。建议进行进一步调查，纳入更多变量。
