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Non-human primates and immunity.

作者信息

André Sonia, Rodrigues Vasco, Picard Morgane, Silvestre Ricardo, Estaquier Jérôme

机构信息

INSERM-U1124, Paris University, Paris, France.

ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal.

出版信息

Cytokine X. 2020 Oct 12;2(4):100038. doi: 10.1016/j.cytox.2020.100038. eCollection 2020 Dec.


DOI:10.1016/j.cytox.2020.100038
PMID:33604562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7885871/
Abstract

In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by infection with protozoan parasites of the genus and classified as one of the neglected tropical diseases.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/861c/7885871/c49f19bcdcf6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/861c/7885871/c49f19bcdcf6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/861c/7885871/c49f19bcdcf6/gr1.jpg

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引用本文的文献

[1]
Overview and Approaches for Handling of Animal Models of Leishmaniasis.

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[2]
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[3]
Role of Cytokines in Experimental and Human Visceral Leishmaniasis.

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本文引用的文献

[1]
Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis.

PLoS Pathog. 2020-4-13

[2]
CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasis.

PLoS Negl Trop Dis. 2020-2-28

[3]
Mitogenic responses of peripheral blood mononuclear cells of vervet monkeys (Cercopithecus aethiops): Apparent role of adherent cells.

Am J Primatol. 1990

[4]
Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis.

Sci Transl Med. 2019-11-20

[5]
Transcriptional Analysis of Human Skin Lesions Identifies Tryptophan-2,3-Deoxygenase as a Restriction Factor for Cutaneous .

Front Cell Infect Microbiol. 2019-10-4

[6]
The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis.

Cytokine. 2018-7-14

[7]
Morphophysiological changes in the splenic extracellular matrix of Leishmania infantum-naturally infected dogs is associated with alterations in lymphoid niches and the CD4+ T cell frequency in spleens.

PLoS Negl Trop Dis. 2018-4-20

[8]
The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.

J Clin Invest. 2018-3-19

[9]
Long-term Clinical Outcomes in Visceral Leishmaniasis/Human Immunodeficiency Virus-Coinfected Patients During and After Pentamidine Secondary Prophylaxis in Ethiopia: A Single-Arm Clinical Trial.

Clin Infect Dis. 2018-1-18

[10]
The Risk and Predictors of Visceral Leishmaniasis Relapse in Human Immunodeficiency Virus-Coinfected Patients in Ethiopia: A Retrospective Cohort Study.

Clin Infect Dis. 2017-10-30

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