André Sonia, Rodrigues Vasco, Picard Morgane, Silvestre Ricardo, Estaquier Jérôme
INSERM-U1124, Paris University, Paris, France.
ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal.
Cytokine X. 2020 Oct 12;2(4):100038. doi: 10.1016/j.cytox.2020.100038. eCollection 2020 Dec.
In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by infection with protozoan parasites of the genus and classified as one of the neglected tropical diseases.
在传染病领域，由于非人灵长类动物（NHP）与人类有着密切的系统发育关系以及相似的生理和解剖系统，它们提供了最佳的人类疾病动物模型。在此，我们总结了非人灵长类动物模型在理解对利什曼病免疫方面的贡献，利什曼病是由利什曼原虫属原生动物寄生虫感染引起的一组疾病，被列为被忽视的热带病之一。
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