Department of Infectious Diseases, Dermatology, Diagnostic Imaging and Radiotherapy, Medical School, São Paulo State University (Unesp), Botucatu, Brazil.
College Anhanguera, Bauru, Brazil.
Am J Primatol. 2022 May;84(4-5):e23376. doi: 10.1002/ajp.23376. Epub 2022 Apr 5.
Wild nonhuman primates (NHP) are considered natural hosts of a protozoan parasite from the genus Leishmania, the etiological agent of leishmaniasis. It is important to study the population of this infectious agent in zoo animals to establish surveillance and control mechanisms in Sorocaba through the application of a One Health approach, this is where human-animal-environment health and disease interface and can aid in the protection of endangered species. This study aimed to identify Leishmania infantum and Leishmania braziliensis in NHP living in a city where leishmaniasis is endemic. DNA was extracted from 48 NHP and analyzed using polymerase chain reaction primers that are specific for the species L. infantum and L. braziliensis. The results of our research revealed the first report of L. infantum and L. braziliensis naturally infecting primates at Sorocaba zoo. One primate from the species Plecturocebus vieirai was positive for L. infantum and five primates (four Alouatta caraya and one Ateles chamek) were positive for L. braziliensis. This indicates a possible role of these animals on the maintenance of these parasites.
野生动物非人类灵长类动物（NHP）被认为是原生动物寄生虫利什曼原虫属的天然宿主，该寄生虫是利什曼病的病原体。通过应用“One Health”方法，研究动物园动物中这种传染性病原体的种群对于在索罗卡巴建立监测和控制机制非常重要，这是人类-动物-环境健康和疾病界面的所在地，可以帮助保护濒危物种。本研究旨在确定生活在利什曼病流行地区的 NHP 中是否存在婴儿利什曼原虫和巴西利什曼原虫。从 48 只 NHP 中提取 DNA，并使用针对 L. infantum 和 L. braziliensis 物种的聚合酶链反应引物进行分析。我们的研究结果首次报告了在索罗卡巴动物园中，婴儿利什曼原虫和巴西利什曼原虫自然感染灵长类动物。一种来自 Plecturocebus vieirai 物种的灵长类动物对婴儿利什曼原虫呈阳性，五只灵长类动物（四只 Alouatta caraya 和一只 Ateles chamek）对巴西利什曼原虫呈阳性。这表明这些动物可能在维持这些寄生虫方面发挥作用。
