经颅直流电刺激对业余跑步者肌肉疲劳的影响:随机、假对照、三盲、交叉研究方案研究。

Effects of Transcranial Direct Current Stimulation on Muscle Fatigue in Recreational Runners: Randomized, Sham-Controlled, Triple-Blind, Crossover Study-Protocol Study.

机构信息

From the Universidade Nove de Julho-UNINOVE, São Paulo-SP, Brazil (LU, ECPL-J, PRVdP, MHFC, JCFC, FIC); and Universidade Federal do ABC-UFABC-São Bernardo do Campo, São Paulo-SP, Brazil (DBC, AFB, RJDM, AHO).

出版信息

Am J Phys Med Rehabil. 2022 Mar 1;101(3):279-283. doi: 10.1097/PHM.0000000000001721.

Abstract

OBJECTIVES

The aim of this study is to evaluate the effects of transcranial direct current stimulation (tDCS) on central and peripheral fatigue in recreational runners.

DESIGN

This is a clinical randomized, sham-controlled, triple-blind, crossover study. Twenty adult runners will be randomized on the first day of the intervention to receive active or sham tDCS before fatigue protocol. After 1 wk, the participants will receive the opposite therapy to the one that they received on the first day. The tDCS, 2 mA, will be applied for 20 mins over the motor cortex. The fatigue protocol will be performed after tDCS, in which the participant should perform concentric knee flexion/extension contractions until reaching three contractions at only 50% of maximum voluntary contraction. Central fatigue will be evaluated with the motor evoked potential of the quadriceps muscle; peripheral fatigue with the peak torque (N.m) using an isokinetic dynamometer; the electrical activity of the quadriceps muscle using surface electromyography (Hz); blood lactate level (mmol/L); and the subjective perception of effort (Borg scale). All evaluations will be repeated before and after the interventions.

CONCLUSION

This study will evaluate the effect of tDCS on fatigue in runners, possibly determining an application protocol for this population.

摘要

目的

本研究旨在评估经颅直流电刺激(tDCS)对休闲跑者中枢和外周疲劳的影响。

设计

这是一项临床随机、假刺激对照、三盲、交叉研究。20 名成年跑者将在干预的第一天随机分为接受 tDCS 或假刺激组,然后在 1 周后接受与第一天相反的治疗。tDCS 强度为 2 mA,将在运动皮质上应用 20 分钟。tDCS 后将进行疲劳协议,在此期间,参与者应进行等长膝关节屈伸收缩,直到仅以最大自主收缩的 50%达到三次收缩。使用等速测力计评估中枢疲劳时采用股四头肌的运动诱发电位;外周疲劳采用峰值扭矩(N.m);使用表面肌电图(Hz)评估股四头肌的电活动;血乳酸水平(mmol/L);以及努力的主观感知(Borg 量表)。所有评估将在干预前后重复进行。

结论

本研究将评估 tDCS 对跑步者疲劳的影响,可能为该人群确定一种应用方案。

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