Cardio-Oncology Service, Royal Brompton Hospital, London, UK.
Service of Cardiology, Department of Internal Medicine, UANL University Hospital, Monterrey, Nuevo Leon, México.
Curr Opin Support Palliat Care. 2021 Jun 1;15(2):134-140. doi: 10.1097/SPC.0000000000000544.
Cardiovascular comorbidity among cancer patients is a growing clinical problem with the dramatic improvements in cancer survival. Cardio-oncology has developed as a new medical field dedicated to addressing the complex issues faced by patients who have both cancer and cardiovascular disease. This article explains to the reader what cardio-oncology services provide and the nature of cardiovascular problems caused by the growing array of modern cancer therapies.
The list of potentially cardiotoxic cancer therapeutic agents is ever growing and dedicated cardio-oncology experts are required to tackle cardiovascular complications with minimal delay to necessary cancer therapy. Cardio-oncology services originated in academic centres but are now being set up around the world in all hospitals and clinics that provide care to cancer patients. Cardio-oncology plays an increasingly active role at every stage of cancer therapy including baseline risk assessment pretreatment, surveillance and prevention during treatment, response to acute complications and assessment in survivors post cardiotoxic treatments. New treatment strategies exist to optimize cancer treatment so it can be completed safely.
In the present review, we explore the rationale, aims and roles of cardio-oncology, as well as future directions, which will certainly require multidisciplinary international collaboration.
随着癌症患者生存率的显著提高,心血管合并症在癌症患者中已成为一个日益严重的临床问题。肿瘤心脏病学是一个新兴的医学领域,致力于解决同时患有癌症和心血管疾病患者所面临的复杂问题。本文旨在向读者解释肿瘤心脏病学服务提供的内容以及一系列现代癌症疗法所引起的心血管问题的性质。
潜在的心脏毒性癌症治疗药物的种类不断增加,需要专门的肿瘤心脏病学专家尽快解决心血管并发症,以免延误必要的癌症治疗。肿瘤心脏病学服务最初起源于学术中心,但现在全世界所有为癌症患者提供治疗的医院和诊所都在设立肿瘤心脏病学服务。肿瘤心脏病学在癌症治疗的各个阶段都发挥着越来越积极的作用,包括基线风险评估、治疗前、治疗期间的监测和预防、急性并发症的反应以及心脏毒性治疗后的幸存者评估。目前已经存在优化癌症治疗的新策略,以确保治疗的安全性。
在本次综述中,我们探讨了肿瘤心脏病学的基本原理、目标和作用,以及未来的发展方向,这肯定需要多学科的国际合作。