结节病的眼睑多面受累。

Multiple Faces of Eyelid Involvement in Sarcoidosis.

机构信息

Division of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo - EPM/UNIFESP, São Paulo, Brazil.

出版信息

Ocul Immunol Inflamm. 2022 May 19;30(4):925-929. doi: 10.1080/09273948.2020.1853782. Epub 2021 Feb 19.

DOI:10.1080/09273948.2020.1853782

PMID:33606589

Abstract

PURPOSE

To report three cases of eyelid involvement by sarcoidosis. In one of them, it mimicked a malignant lesion.

METHODS

Retrospective case reports.

RESULTS

A 73-year-old man presented with destruction of the left lower eyelid for 2 years. He had granulomatous uveitis in the left eye. Chest CT scan showed parenchymal abnormalities that could correspond to sarcoidosis. Skin biopsy revealed noncaseating granuloma. Oral and topical corticosteroids resulted in improvement of the condition. A 72-year-old female patient presented with cutaneous infiltration of the left upper eyelid for 1 month. Biopsy was consistent with sarcoidosis. Endobronchial biopsies showed interstitial fibrosis. Oral prednisone improved the condition. A 65-year-old female patient presented with edema of the right upper eyelid for 2 months. Full-thickness biopsy showed granuloma without necrosis. There was an improvement with oral steroid.

CONCLUSION

Although eyelid involvement in sarcoidosis is uncommon, different forms of presentation, including destructive lesions, can be observed.

摘要

目的

报告三例由结节病引起的眼睑受累病例。其中一例表现类似恶性病变。

方法

回顾性病例报告。

结果

一名 73 岁男性，左眼葡萄膜炎 2 年，左眼出现下眼睑破坏。胸部 CT 扫描显示肺实质异常，可能与结节病有关。皮肤活检显示非坏死性肉芽肿。口服和局部皮质类固醇治疗后病情改善。一名 72 岁女性，左上眼睑皮肤浸润 1 个月。活检符合结节病。支气管内活检显示间质性纤维化。口服泼尼松改善了病情。一名 65 岁女性，右上眼睑水肿 2 个月。全层活检显示无坏死的肉芽肿。口服类固醇治疗后有改善。