Department of Human Movement Sciences, @AgeAmsterdam, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, the Netherlands.
Department of Medicine and Aged Care, @AgeMelbourne, The Royal Melbourne Hospital, The University of Melbourne, Victoria, Australia.
Ageing Res Rev. 2021 May;67:101266. doi: 10.1016/j.arr.2021.101266. Epub 2021 Feb 16.
Engaging in physical activity (PA) and avoiding sedentary behavior (SB) are important for healthy ageing with benefits including the mitigation of disability and mortality. Whether benefits extend to key determinants of disability and mortality, namely muscle strength and muscle power, is unclear.
This systematic review aimed to describe the association of objective measures of PA and SB with measures of skeletal muscle strength and muscle power in community-dwelling older adults.
Six databases were searched from their inception to June 21, 2020 for articles reporting associations between objectively measured PA and SB and upper body or lower body muscle strength or muscle power in community dwelling adults aged 60 years and older. An overview of associations was visualized by effect direction heat maps, standardized effect sizes were estimated with albatross plots and summarized in box plots. Articles reporting adjusted standardized regression coefficients (β) were included in meta-analyses.
A total of 112 articles were included representing 43,796 individuals (range: 21 to 3726 per article) with a mean or median age from 61.0 to 88.0 years (mean 56.4 % female). Higher PA measures and lower SB were associated with better upper body muscle strength (hand grip strength), upper body muscle power (arm curl), lower body muscle strength, and lower body muscle power (chair stand test). Median standardized effect sizes were consistently larger for measures of PA and SB with lower compared to upper body muscle strength and muscle power. The meta-analyses of adjusted β coefficients confirmed the associations between total PA (TPA), moderate-to-vigorous PA (MVPA) and light PA (LPA) with hand grip strength (β = 0.041, β = 0.057, and β = 0.070, respectively, all p ≤ 0.001), and TPA and MVPA with chair stand test (β = 0.199 and β = 0.211, respectively, all p ≤ 0.001).
Higher PA and lower SB are associated with greater skeletal muscle strength and muscle power, particularly with the chair stand test.
进行身体活动 (PA) 和避免久坐行为 (SB) 对于健康老龄化很重要，其益处包括减轻残疾和死亡率。目前尚不清楚这些益处是否会扩展到残疾和死亡率的关键决定因素，即肌肉力量和肌肉功率。
本系统评价旨在描述社区居住的老年人中客观测量的 PA 和 SB 与骨骼肌力量和肌肉功率测量值之间的关联。
从数据库建立到 2020 年 6 月 21 日，共检索了 6 个数据库，以检索报告社区居住的成年人中客观测量的 PA 和 SB 与上半身或下半身肌肉力量或肌肉功率之间关联的文章。通过效应方向热图直观地展示关联，使用 albatross 图估计标准化效应大小，并汇总在箱线图中。纳入了报告调整后标准化回归系数 (β) 的文章进行荟萃分析。
共纳入 112 篇文章，共涉及 43796 人（每篇文章 21 至 3726 人），平均年龄为 61.0 至 88.0 岁（平均 56.4%为女性）。较高的 PA 测量值和较低的 SB 与上半身肌肉力量（握力）、上半身肌肉力量（臂弯举）、下半身肌肉力量和下半身肌肉力量（坐站测试）更好相关。与上半身肌肉力量和肌肉功率相比，PA 和 SB 测量值的标准化效应大小中位数始终更大。调整后的 β 系数荟萃分析证实了 TPA、中高强度 PA（MVPA）和低强度 PA（LPA）与握力之间的关联（β=0.041、β=0.057 和 β=0.070，均 p≤0.001），以及 TPA 和 MVPA 与坐站测试之间的关联（β=0.199 和 β=0.211，均 p≤0.001）。
较高的 PA 和较低的 SB 与更大的骨骼肌力量和肌肉功率相关，尤其是与坐站测试相关。
