University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK
University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Open Heart. 2021 Feb;8(1). doi: 10.1136/openhrt-2019-001211.
The coexistence of two complex physiologies such as Fontan and pregnancy is still not fully understood. We aim to add a unique and essential knowledge to help our colleagues in the management of Fontan patients that undergo pregnancy as well as the fetus and the placenta perfusion.
We analyse the coexistence of Fontan and pregnancy physiology on a complex case of a woman with hypoplastic left heart syndrome palliated with a univentricular repair who became pregnant, delivered very prematurely and had atypical placental findings.
Histopathological analysis of the placenta could help us to refine the understanding of Fontan physiology adaptation during pregnancy, predict women and fetal outcomes as well as to plan a better pre-pregnancy status. However, further evidence is needed in order to reach a more solid and unified conclusion.
法洛四联症（Fontan）和妊娠这两种复杂生理状态并存的情况仍未被完全理解。我们旨在增加一个独特而必要的知识，以帮助我们的同事管理经历妊娠的 Fontan 患者以及胎儿和胎盘灌注。
我们分析了一位患有左心发育不全综合征的女性的复杂病例，她接受了单心室修复术姑息治疗后怀孕，早产且胎盘表现不典型。
胎盘的组织病理学分析可以帮助我们更好地理解 Fontan 生理适应在妊娠期间的情况，预测女性和胎儿的结局，并为更好的孕前状态做好规划。然而，需要进一步的证据来得出更坚实和统一的结论。
