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妊娠期肝病:一个具有挑战性的临床问题。

Liver Disease During Pregnancy: A Challenging Clinical Issue.

机构信息

Department of Gastroenterology, University Hospital Center (UHC) Rijeka, School of Medicine, University of Rijeka, Rijeka, Croatia.

Department of Gastroenterology, University Hospital Merkur, School of Medicine, University of Zagreb, Zagreb, Croatia.

出版信息

Med Sci Monit. 2018 Jun 15;24:4080-4090. doi: 10.12659/MSM.907723.

Abstract

One of the least studied topics in the field of obstetrics is liver disease during pregnancy, which creates a challenge for both gynecologists and hepatologists. Approximately 3% of pregnant women are affected by some form of liver disease during pregnancy. Some of these conditions can be fatal for both the mother and child. In addition, 3 types of liver disease need to be differentiated during pregnancy. One type is liver disease directly related to pregnancy, which can occur at a specific time during pregnancy. Another type is liver disease not related to pregnancy, which can occur at any time, such as viral- or drug-induced hepatitis. Furthermore, pregnancy can occur in women with pre-existing liver disease. It is essential that the clinicians are familiar with this disorder so they can respond promptly and appropriately in all of these situations, especially when emergency delivery is needed and must not be postponed.

摘要

在妇产科领域,研究最少的课题之一是妊娠期间的肝脏疾病,这给妇科医生和肝病专家都带来了挑战。大约 3%的孕妇在妊娠期间会受到某种形式的肝脏疾病的影响。其中一些疾病对母亲和孩子都是致命的。此外,在妊娠期间需要区分 3 种类型的肝脏疾病。一种是与妊娠直接相关的肝脏疾病,它可能发生在妊娠的特定时间。另一种是与妊娠无关的肝脏疾病,它可能随时发生,如病毒性或药物性肝炎。此外,患有预先存在的肝脏疾病的妇女也可能怀孕。临床医生必须熟悉这种疾病,以便在所有这些情况下都能迅速而适当地做出反应,特别是在需要紧急分娩且不能推迟的情况下。

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