Suppr超能文献

妊娠期肝病:一个具有挑战性的临床问题。

Liver Disease During Pregnancy: A Challenging Clinical Issue.

机构信息

Department of Gastroenterology, University Hospital Center (UHC) Rijeka, School of Medicine, University of Rijeka, Rijeka, Croatia.

Department of Gastroenterology, University Hospital Merkur, School of Medicine, University of Zagreb, Zagreb, Croatia.

出版信息

Med Sci Monit. 2018 Jun 15;24:4080-4090. doi: 10.12659/MSM.907723.

Abstract

One of the least studied topics in the field of obstetrics is liver disease during pregnancy, which creates a challenge for both gynecologists and hepatologists. Approximately 3% of pregnant women are affected by some form of liver disease during pregnancy. Some of these conditions can be fatal for both the mother and child. In addition, 3 types of liver disease need to be differentiated during pregnancy. One type is liver disease directly related to pregnancy, which can occur at a specific time during pregnancy. Another type is liver disease not related to pregnancy, which can occur at any time, such as viral- or drug-induced hepatitis. Furthermore, pregnancy can occur in women with pre-existing liver disease. It is essential that the clinicians are familiar with this disorder so they can respond promptly and appropriately in all of these situations, especially when emergency delivery is needed and must not be postponed.

摘要

在妇产科领域,研究最少的课题之一是妊娠期间的肝脏疾病,这给妇科医生和肝病专家都带来了挑战。大约 3%的孕妇在妊娠期间会受到某种形式的肝脏疾病的影响。其中一些疾病对母亲和孩子都是致命的。此外,在妊娠期间需要区分 3 种类型的肝脏疾病。一种是与妊娠直接相关的肝脏疾病,它可能发生在妊娠的特定时间。另一种是与妊娠无关的肝脏疾病,它可能随时发生,如病毒性或药物性肝炎。此外,患有预先存在的肝脏疾病的妇女也可能怀孕。临床医生必须熟悉这种疾病,以便在所有这些情况下都能迅速而适当地做出反应,特别是在需要紧急分娩且不能推迟的情况下。

相似文献

1
Liver Disease During Pregnancy: A Challenging Clinical Issue.
Med Sci Monit. 2018 Jun 15;24:4080-4090. doi: 10.12659/MSM.907723.
2
Liver abnormalities in pregnancy.
Best Pract Res Clin Gastroenterol. 2013 Aug;27(4):565-75. doi: 10.1016/j.bpg.2013.06.015.
3
Liver disease in pregnancy: Medical aspects and their implications for mother and child.
Ann Hepatol. 2019 Jul-Aug;18(4):553-562. doi: 10.1016/j.aohep.2019.04.009. Epub 2019 May 6.
5
Liver disease in pregnancy.
Med Clin North Am. 1989 Jul;73(4):1041-6. doi: 10.1016/s0025-7125(16)30652-6.
6
[Icterus in pregnancy].
Med Chir Dig. 1973;2(6):337-44.
7
Pregnancy-associated liver disorders.
Dig Dis Sci. 2008 Sep;53(9):2334-58. doi: 10.1007/s10620-007-0167-9. Epub 2008 Feb 7.
8
Pregnancy-associated severe liver dysfunction.
Crit Care Clin. 2004 Oct;20(4):763-76, xi. doi: 10.1016/j.ccc.2004.05.006.
9
Pregnancy and liver disease.
Forum (Genova). 1998 Jan-Mar;8(1):42-58.
10
Pregnancies complicated by liver disease and liver dysfunction.
Obstet Gynecol Clin North Am. 1992 Dec;19(4):745-63.

引用本文的文献

1
Intrahepatic Cholestasis of Pregnancy: Diagnosis, Management, and Future Directions-A Review of the Literature.
Diagnostics (Basel). 2025 Aug 10;15(16):2002. doi: 10.3390/diagnostics15162002.
2
Imaging of pregnancy-related liver diseases.
ILIVER. 2023 Mar 4;2(1):56-66. doi: 10.1016/j.iliver.2023.02.003. eCollection 2023 Mar.
8
A Narrative Review of Oxidative Stress and Liver Disease in Pregnancy: The Role of Antioxidants.
Cureus. 2024 Jul 17;16(7):e64714. doi: 10.7759/cureus.64714. eCollection 2024 Jul.
9
Obstetric cholestasis and its impact on the maternal outcome.
Arch Gynecol Obstet. 2024 Sep;310(3):1587-1592. doi: 10.1007/s00404-024-07592-1. Epub 2024 Jul 10.
10
Evaluation of Liver Enzymes in Normal Pregnancies in a University Hospital of Zabol Iran: A Cross-Sectional Study.
J Family Reprod Health. 2023 Sep;17(3):185-190. doi: 10.18502/jfrh.v17i3.13542.

本文引用的文献

1
Severe reduction of free-form ADAMTS13, unbound to von Willebrand factor, in plasma of patients with HELLP syndrome.
Blood Adv. 2017 Aug 23;1(20):1628-1631. doi: 10.1182/bloodadvances.2017006767. eCollection 2017 Sep 12.
2
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection.
J Hepatol. 2017 Aug;67(2):370-398. doi: 10.1016/j.jhep.2017.03.021. Epub 2017 Apr 18.
3
Acute Fatty Liver Disease of Pregnancy: Updates in Pathogenesis, Diagnosis, and Management.
Am J Gastroenterol. 2017 Jun;112(6):838-846. doi: 10.1038/ajg.2017.54. Epub 2017 Mar 14.
4
Hepatitis B Management in the Pregnant Patient: An Update.
J Clin Transl Hepatol. 2016 Sep 28;4(3):241-247. doi: 10.14218/JCTH.2016.00014. Epub 2016 Sep 25.
5
AISF position paper on liver disease and pregnancy.
Dig Liver Dis. 2016 Feb;48(2):120-37. doi: 10.1016/j.dld.2015.11.004. Epub 2015 Nov 14.
6
Pregnancy and liver disease.
J Hepatol. 2016 Apr;64(4):933-45. doi: 10.1016/j.jhep.2015.11.030. Epub 2015 Nov 30.
8
Liver disease in pregnancy.
Taiwan J Obstet Gynecol. 2015 Oct;54(5):475-82. doi: 10.1016/j.tjog.2015.01.004.
9
Review of a challenging clinical issue: Intrahepatic cholestasis of pregnancy.
World J Gastroenterol. 2015 Jun 21;21(23):7134-41. doi: 10.3748/wjg.v21.i23.7134.
10
The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP.
Pregnancy Hypertens. 2014 Apr;4(2):97-104. doi: 10.1016/j.preghy.2014.02.001. Epub 2014 Feb 15.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验