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六价铬:法规和健康影响。

Hexavalent chromium: Regulation and health effects.

机构信息

Escuela Militar de Medicina, Universidad del Ejército y Fuerza Aérea, Secretaría de la Defensa Nacional, Mexico; Laboratorio de Morfología Celular, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico.

Laboratorio de Toxicología y Química y Toxicología Forense, Ciencia Forense, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico.

出版信息

J Trace Elem Med Biol. 2021 May;65:126729. doi: 10.1016/j.jtemb.2021.126729. Epub 2021 Feb 12.

Abstract

Despite the knowledge about heavy metals toxicity on humans, its use is widely spread mainly for industrial processes. Chromium is an element that belongs to this group and although it is present in our daily diet, it can also be harmful for humans, causing skin allergies and increasing the risk of lung cancer, among other health effects reported. In this review, we highlight its nutritional role, its toxicokinetic and toxicodynamic in humans, its regulation in the industry and the biomonitoring proposal of this element in blood and urine samples with the aim to control the level of exposure of the workers in military industry and also of the general population.

摘要

尽管人们已经了解重金属对人体的毒性,但它们仍被广泛应用于工业生产过程。铬就是属于这一类的元素,尽管它存在于我们的日常饮食中,但也可能对人体有害,导致皮肤过敏,并增加患肺癌等其他健康问题的风险。在本次综述中,我们重点介绍了铬的营养作用、在人体内的毒代动力学和毒效动力学、工业领域的监管以及血液和尿液样本中该元素的生物监测建议,目的是控制军工行业工人和一般人群的暴露水平。

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